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Hydralazine
go.drugbank.com/drugs/DB01275ApprovedInvestigationalOriginally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. … [A186820,L8782,L8785] Hydralazine is no longer a first line therapy for these indications since the development of newer antihypertensive medications.
Mixtures: Ser-Ap-Es, Ser-AP-ES TabCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A InhibitorsFluoroacetic acid F-18
go.drugbank.com/drugs/DB15202InvestigationalFluoroacetic acid F-18 is under investigation in clinical trial NCT01320787 (18-F-Fluoroacetate as PET Imaging Agent).
Synonyms: Fluoroacetic acid F-18Ciltacabtagene autoleucel
go.drugbank.com/drugs/DB16738ApprovedInvestigationalIt is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000,[L40749] and is variable in its presentation - some patients may remain entirely asymptomatic, while others may experience … [L40739] Patient T-cells are reprogrammed with a transgene encoding a specific chimeric antigen receptor (CAR) which features two BCMA-targeting single-domain antibodies.
Synonyms: Autologous bi-epitope BCMA-targeted CAR T-cellsSufentanil
go.drugbank.com/drugs/DB00708ApprovedInvestigationalSufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. … This route of administration is intended to be a simple, effective, non-invasive analgesic option to enable healthcare professionals to rapidly manage acute pain without difficult intravenous or epidural
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 舒芬太尼, N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamideDichlorotetrafluoroethane
go.drugbank.com/drugs/DB20118ApprovedWithdrawnDichlorotetrafluoroethane is a small molecule drug. Dichlorotetrafluoroethane has a monoisotopic molecular weight of 169.93 Da.
Mixtures: Flouro Ethyl AerProducts: Pharmaethyl AerSulindac Action Pathway
smpdb.ca/view/SMP0000094Drug actionSulindac, sold as Clinoril, is a non-steroidal anti-inflammatory drug (NSAID). These drugs are typically used to treat conditions associated with pain and inflammation, such as rheumatoid arthritis, headaches or migraines, and dysmenorrh...
Enzymes: Prostaglandin E synthaseBromfenac Action Pathway
smpdb.ca/view/SMP0000102Drug actionBromfenac (also named Prolensa, Bromday or Xibrom) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to reduce ocular inflammation and pain after cataract surgery. Bromfenac is also a type of ophthalmic anti-inflammatory m...
Enzymes: Prostaglandin E synthaseMefenamic Acid Action Pathway
smpdb.ca/view/SMP0000109Drug actionMefenamic acid (also named Ponstel) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to relieve pain (analgesic) and reduce fever (antipyretic). Mefenamic acid can block prostaglandin synthesis by the action of inhibition...
Drugs: Glutamic acid · Glutathione · Mefenamic acid · Dinoprostone · Calcium · Magnesium cation +5 moreEnzymes: Prostaglandin E synthaseOxaprozin Action Pathway
smpdb.ca/view/SMP0000113Drug actionOxaprozin (also named Daypro, Dayrun) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to relieve pain (analgesic) and reduce fever (antipyretic). Oxaprozin is also a type of ophthalmic anti-inflammatory medicines which m...
Enzymes: Prostaglandin E synthaseNaproxen Action Pathway
smpdb.ca/view/SMP0000120Drug actionNaproxen (also named Aleve and Naprosyn) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to relieve pain (analgesic) and reduce fever (antipyretic). Naproxen is also a type of ophthalmic anti-inflammatory medicines. Napr...
Enzymes: Prostaglandin E synthase