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Displaying results 2771 - 2780 of 10000 in total
  1. Drug

    Dydrogesterone

    go.drugbank.com/drugs/DB00378
    ApprovedInvestigationalWithdrawn

    A synthetic progestational hormone with no androgenic or estrogenic properties. … Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.

    Mixtures: Femoston conti 1 mg/5 mg Filmtabletten, FEMOSTON CONTI 1/5Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  2. Drug

    Tetracaine

    go.drugbank.com/drugs/DB09085
    ApprovedInvestigationalVet approved

    Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.

    Mixtures: Pliaglis 70 mg/g + 70 mg/g Creme, Pliaglis 70 mg/g + 70 mg/g creamCategories: Antipruritics and Local Anesthetics, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use
  3. Drug

    Medronic acid

    go.drugbank.com/drugs/DB14078
    ApprovedInvestigational

    Products: MON MDP KIT 10 MG IV ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 5 ADET, DRAXIMAGE® MDP
  4. Drug

    Cefalotin

    go.drugbank.com/drugs/DB00456
    ApprovedVet approvedWithdrawn

    Cefalotin is a cephalosporin antibiotic.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid, 7-(Thiophene-2-acetamido)cephalosporin
  5. Drug

    Tolevamer

    go.drugbank.com/drugs/DB01344
    Approved

    It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. … Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels.

    Synonyms: poly(styrene-4-sulfonic acid)International brands: Resonium A
  6. Drug

    KOS-2187

    go.drugbank.com/drugs/DB05946
    Experimental

    KOS-2187, a novel erythromycin-based motilin agonist, or motilide, as a clinical candidate for the treatment of gastrointestinal motility disorders such as gastroparesis and gastroesophageal reflux disease

    Synonyms: (3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-7,10,12,13-tetrahydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy-6-[3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl, -14-phenyl-oxacyclotetradecan-2-one
  7. Drug

    Phenylephrine

    go.drugbank.com/drugs/DB00388
    ApprovedInvestigational

    Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and induce local vasoconstriction.

    Synonyms: (−)-m-hydroxy-α-(methylaminomethyl)benzyl alcohol, l-(3-Hydroxyphenyl)-N-methylethanolamineMixtures: PİRETİKOL PLUS 160 MG/5 ML+1 MG/5 ML+2.5 MG/5 ML PEDİATRİK ŞURUP, 100 ML, CORSAL 120 MG + 5 MG + 2 MG/5 ML SURUP, 120 ML
  8. Drug

    Vecuronium

    go.drugbank.com/drugs/DB01339
    ApprovedInvestigational

    A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. … Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or

    Categories: P-glycoprotein substratesProducts: NORCURON 10 MG, VECRON 10 MG İ.V. ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL
  9. Drug

    Nivolumab

    go.drugbank.com/drugs/DB09035
    ApprovedInvestigational

    Nivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). … [L12129] This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation _S228P_ for additional stability and reduced variability.

    Mixtures: OPDUALAG® SOLUCION INYECTABLECategories: Immunoglobulin G, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors
  10. Drug

    Clozapine

    go.drugbank.com/drugs/DB00363
    ApprovedInvestigational

    [A256708] Clozapine displays affinity to various neuroreceptors with a particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and deeming it "atypical … [A185747] However, its promiscuity toward the muscarinic and adrenergic receptors can result in other side effects, notably gastrointestinal hypomotility and orthostatic hypotension. [L905,A215552].

    Categories: Adrenergic alpha-1 Receptor Antagonists, Diazepines, Oxazepines, Thiazepines and OxepinesProducts: CLONEX 100 MG TABLET, 50 ADET, LEPONEX 100 MG TABLET, 50 ADET