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Fospropofol Action Pathway
smpdb.ca/view/SMP0126836Drug actionFospropofol, a sedative-hypnotic agent, serves as a solution for monitored anesthesia care (MAC) sedation in adults undergoing diagnostic or therapeutic procedures. As a water-soluble prodrug, it transforms into propofol within the liver...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate +3 moreEnzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Midazolam Action Pathway
smpdb.ca/view/SMP0125055Drug actionMidazolam is a short-acting injectable benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders. Midazolam allosterically binds on the benzodiazepine receptors in the post-synaptic GABA-A ligand...
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Bromazepam Action Pathway
smpdb.ca/view/SMP0125070Drug actionBromazepam is a short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety. Bromazepam is a lipophilic, long-acting benzodiazepine and with sedative, hypnotic, anxiolytic and skeletal mu...
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Flurazepam Action Pathway
smpdb.ca/view/SMP0126129Drug actionFlurazepam is a long-acting benzodiazepine with a rapid onset of action that is commonly used to treat insomnia. It can be found under the brand name Dalmane, and it is a benzodiazepine derivative used mainly as a hypnotic. It does not a...
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Flumazenil Action Pathway
smpdb.ca/view/SMP0126152Drug actionFlumazenil is a benzodiazepine antagonist that is used for the complete or partial reversal of the sedative effects caused by benzodiazepines in various clinical settings, such as induced general anesthesia for diagnostic and therapeutic...
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Diazepam Action Pathway
smpdb.ca/view/SMP0124471Drug actionIt binds to an allosteric site between the alpha and gamma subunits of the receptor increasing the inhibitory effects of GABA.
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Meprobamate Action Pathway
smpdb.ca/view/SMP0126134Drug actionMeprobamate is an anxiolytic drug used for the short-term management of anxiety symptoms. A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct e...
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Desflurane GABA(A) Anesthetic Action Pathway
smpdb.ca/view/SMP0126151Drug actionDesflurane is a general inhalation anesthetic for inpatient and outpatient surgery in adults. It can be found under the brand name Suprane, and is a volatile anesthetic that is more rapidly cleared and less metabolized than previous inha...
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Isoflurane GABA(A) Anesthetic Action Pathway
smpdb.ca/view/SMP0126162Drug actionIsoflurane is an inhaled general anesthetic used in surgery. It can be found under the brand names Forane and Terrell and is a stable, non-explosive inhalation anesthetic, relatively free from significant side effects. Isoflurane is a ge...
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Lorazepam Action Pathway
smpdb.ca/view/SMP0125053Drug actionLorazepam is a short-acting benzodiazepine commonly used for the short-term relief of anxiety symptoms related to anxiety disorders and anxiety associated with depressive symptoms such as anxiety-associated insomnia. It is as well used a...
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2