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DNA polymerase III subunit tau

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3'-5' exonuclease activity. … Primed DNA is recognized, ATP is hydrolyzed releasing the gamma complex and closing the beta sliding clamp ring around the primed DNA (PubMed:9927437).

Endonuclease III-like protein 1

Primarily recognizes and repairs oxidative base damage of pyrimidines. Also has 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. … The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site.

Class III cytochrome C family protein

Beta-ketoacyl-[acyl-carrier-protein] synthase III

Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Has some substrate specificity for acetyl-CoA. … Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.

Beta-ketoacyl-[acyl-carrier-protein] synthase III

Propionyl-CoA and isobutyryl-CoA were the two most preferred substrates, although acetyl-CoA and butyryl-CoA could also be accepted and elongated (PubMed:11732905). … Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities (PubMed:11732905).

Beta-ketoacyl-[acyl-carrier-protein] synthase III

Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids. … Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.

DNA-directed RNA polymerase III subunit RPC1

During transcription initiation, Pol III is recruited to DNA promoters type I, II or III with the help of general transcription factors and other specific initiation factors. … Pol III plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as a nuclear and cytosolic DNA sensor involved in innate immune response.

Mycobacterial beta-ketoacyl-[acyl-carrier-protein] synthase III

Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities (PubMed:10840036, PubMed:11278743, PubMed:16040614). … Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.

Low affinity immunoglobulin gamma Fc region receptor III-A

Binds antigen-IgG complexes generated upon infection and triggers NK cell-dependent cytokine production and degranulation to limit viral load and propagation. … Mediates enhanced opsonization and ADCC in response to afucosylated IgGs (PubMed:34485821, PubMed:28566370)

Low affinity immunoglobulin gamma Fc region receptor III-B

Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis.