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Displaying results 21 - 30 of 17651 in total
  1. Drug

    Periciazine

    go.drugbank.com/drugs/DB01608
    Approved

    Pericyazine, like other phenothiazines, is presumed to act principally in the subcortical areas, by producing what has been described as a central adrenergic blockade.

    Categories: Adrenergic alpha-1 Receptor AntagonistsSynonyms: 2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazine, Cyano-3 ((hydroxy-4 piperidyl-1)-3 propyl)-10 phenothiazine
  2. Drug

    Influenza A virus A/Brisbane/10/2010 live (attenuated) antigen

    go.drugbank.com/drugs/DB16517
    Approved

    Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen

    Synonyms: Influenza A virus A/Brisbane/10/2010 (H1N1) whole, Influenza A virus A/Brisbane/10/2010 (H1N1) wild type
  3. Drug

    10-hydroxycamptothecin

    go.drugbank.com/drugs/DB12385
    Experimental

    10-hydroxycamptothecin is under investigation in clinical trial NCT00956787 (Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)).

  4. Drug

    Dolastatin 10

    go.drugbank.com/drugs/DB12730
    Investigational

    Dolastatin 10 has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Liver Cancer, and Kidney Cancer, among others.

  5. Drug

    Magnesium acetate

    go.drugbank.com/drugs/DB13996
    Approved

    Synonyms: Mg(II) acetate, Acetic acid, magnesium salt (2:1)Mixtures: AMINOPLASMAL-10% E INFUSION, Normosol-M and Dextrose
  6. Drug

    PQ-10

    go.drugbank.com/drugs/DB08391
    Experimental

  7. Drug

    Prochlorperazine

    go.drugbank.com/drugs/DB00433
    ApprovedInvestigationalVet approved

    [L6637] Prochlorperazine was first developed in the 1950s [L6643] and was first approved by the FDA in 1956. … [label] It mainly works by depressing the chemoreceptor trigger zone and blocking D2 dopamine receptors in the brain. It was shown to also block histaminergic, cholinergic and noradrenergic receptors.

    Synonyms: 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine, 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazineProducts: STEMETIL INJECTION 12.5 mg/ml, PROCHLOR TABLETS 5 mg
  8. Drug

    Methotrimeprazine

    go.drugbank.com/drugs/DB01403
    Approved

    A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlo...

    Synonyms: (-)-(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine, (-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazineCategories: Adrenergic alpha-1 Receptor Antagonists
  9. Drug

    Colchiceine

    go.drugbank.com/drugs/DB15534
    Approved

    Colchiceine is one of several metabolites of the anti-gout medication colchicine.

    Synonyms: 10-O-demethylcolchicine, O10-Demethylcolchicine
  10. Drug

    Nicergoline

    go.drugbank.com/drugs/DB00699
    Approved

    An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease.

    Categories: Adrenergic alpha-1 Receptor AntagonistsSynonyms: 10-methoxy-1,6-dimethylergoline-8β-methanol 5-bromonicotinate, (8β)-10-methoxy-1,6-dimethylergoline-8-methanol 5-bromo-3-pyridinecarboxylate (ester)