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Displaying results 21 - 30 of 130 in total
  1. Pathway

    Minaprine Amine oxidase Norepinephrine Antidepressant Action Pathway

    smpdb.ca/view/SMP0126684
    Drug action

    The first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine. … The second one, the B isoform, breakdowns phenylethylamine, norepinephrine, epinephrine, dopamine, and tyramine. This isoform is found in the extracellular tissues and mostly in the brain.

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · NADH · Sapropterin +8 more
  2. Pathway

    Moclobemide Amine Oxidase Norepinephrine Antidepressant Action Pathway

    smpdb.ca/view/SMP0126685
    Drug action

    The first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine. … The second one, the B isoform, breakdowns phenylethylamine, norepinephrine, epinephrine, dopamine, and tyramine. This isoform is found in the extracellular tissues and mostly in the brain.

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · NADH · Sapropterin +8 more
  3. Pathway

    Doxepin Norepinephrine Reuptake Inhibitor Action Pathway (New)

    smpdb.ca/view/SMP0126355
    Drug action

    Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. It is used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia. Similar to other tricyclic antidepressants, doxepin decreases th...

    Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Tryptophan · Sapropterin · Norepinephrine +7 more
  4. Pathway

    Norepinephrine Alpha 1A Adrenergic Blood Vessel Relaxation Action Pathway

    smpdb.ca/view/SMP0125166
    Drug action

    Norepinephrine is a sympathomimetic that is regularly found to be the primary neurotransmitter in postganglionic neurons.

    Drugs: ATP · Norepinephrine · Calcium · Magnesium cation
  5. Indication

    Severe hypotension

    go.drugbank.com/conditions/DBCOND0118169
    Drugs: Norepinephrine
  6. Indication

    Acute, severe Hypotension

    go.drugbank.com/conditions/DBCOND0142491
    Drugs: Norepinephrine
  7. Drug

    Pseudoephedrine

    go.drugbank.com/drugs/DB00852
    Approved

    Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system. Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first ...

    Mixtures: Hydrocodone bitartrate and pseudoephedrine hydrochloride solution, Hydrocodone Bitartrate, Chlorpheniramine Maleate, and Pseudoephedrine HClCategories: Norepinephrine Releasing Agents
  8. Indication

    Cardiac Arrest

    go.drugbank.com/conditions/DBCOND0031003
    Drugs: Isoprenaline · Norepinephrine
  9. Pathway

    Droxidopa A1-Adrenergic Vasoconstriction Action Pathway

    smpdb.ca/view/SMP0126494
    Drug action

    Droxidopa is an orally active synthetic precursor of norepinephrine that increases the deficient supply of norepinephrine in patients with NOH, thereby improving orthostatic blood pressure and alleviating … Norepinephrine activates the alpha-1 adrenergic receptor which activates the Gq protein cascade.

    Drugs: ATP · Norepinephrine · Calcium · Magnesium cation
  10. Pathway

    Droxidopa B1-Adrenergic Cardiac Muscle Contraction Action Pathway

    smpdb.ca/view/SMP0126078
    Drug action

    Norepinephrine is stored in synaptic storage sites where norepinephrine was already being stored. When the neuron is depolarized, this accumulation of norepinephrine is released into the synapse. … Through the beta-1 adrenergic receptor, the heart is stimulated by norepinephrine.

    Drugs: Pyridoxal phosphate · ATP · Norepinephrine · Calcium · Droxidopa