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Displaying results 21 - 30 of 10000 in total
  1. Target

    ATP synthase F(0) complex subunit a

    go.drugbank.com/bio_entities/BE0009014
    TargetHumans

    Subunit a, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated … With the subunit c (ATP5MC1), forms the proton-conducting channel in the F(0) domain, that contains two crucial half-channels (inlet and outlet) that facilitate proton movement from the mitochondrial intermembrane

    Polypeptides: ATP synthase F(0) complex subunit aSynonyms: Proton-conducting channel, ATP synthase F(0) complex subunit a
  2. Target

    ATP synthase F(0) complex subunit e, mitochondrial

    go.drugbank.com/bio_entities/BE0009021
    TargetHumans

    Part of the complex F(0) domain (PubMed:37244256) … Subunit e, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated

    Polypeptides: ATP synthase F(0) complex subunit e, mitochondrial
  3. Target

    Sodium-dependent neutral amino acid transporter B(0)AT1

    go.drugbank.com/bio_entities/BE0015577
    TransporterTargetHumans

    Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells (PubMed:15286787, PubMed:15286788, PubMed:18424768, PubMed:18484095, PubMed:19185582, PubMed:26240152). This ...

    Polypeptides: Sodium-dependent neutral amino acid transporter B(0)AT1Synonyms: System B(0) neutral amino acid transporter AT1
  4. Target

    Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)

    go.drugbank.com/bio_entities/BE0000423
    TargetTransporterHumans

    Amino acid transporter that plays an important role in the absorption of amino acids in the intestinal tract. Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-depen...

    Polypeptides: Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
  5. Drug

    Neostigmine

    go.drugbank.com/drugs/DB01400
    ApprovedInvestigationalVet approved

    A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine.

    Synonyms: 3-Trimethylammoniumphenyl N,N-dimethylcarbamate, m-TrimethylammoniumphenyldimethylcarbamateProducts: NEOSTIGMINA 0. 5 MG / MLSOLUCION INYECTABLE, Prostigmin Inj 1:400 USP
  6. Indication

    Carcinoma in situ of urinary bladder

    go.drugbank.com/conditions/DBCOND0106378
    Drugs: BCG vaccine · Bacillus calmette-guerin substrain connaught live antigen · Bacillus calmette-guerin substrain tice live antigen · Epirubicin
    Synonyms: Ca bladder stage 0, with cancer in situ, Bladder cancer stage 0, with cancer in situ
  7. Drug

    Metoprolol

    go.drugbank.com/drugs/DB00264
    ApprovedInvestigational

    Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. … [A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527]

    Mixtures: Implicor 50 mg/5 mg Filmtabletten, IMPLICOR FILM-COATED TABLET 50 mg/5 mgCategories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor Antagonists
  8. Target

    Lens fiber major intrinsic protein

    go.drugbank.com/bio_entities/BE0003901
    TargetHumans

    Aquaporins form homotetrameric transmembrane channels, with each monomer independently mediating water transport across the plasma membrane along its osmotic gradient (PubMed:11001937, PubMed:24120416). Specifically expressed in lens fib...

    Synonyms: Aquaporin-0
  9. Drug

    Cholecalciferol

    go.drugbank.com/drugs/DB00169
    ApprovedInvestigationalNutraceutical

    Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation … Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight [L5689].

    Synonyms: Vitamin D 3, Vitamin D-3International brands: Delta-D, Micro-D
  10. Target

    ATP synthase subunit c

    go.drugbank.com/bio_entities/BE0004088
    TargetArthrospira platensis HN01

    F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. … F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral

    Synonyms: ATP synthase F(0) sector subunit c