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Displaying results 3041 - 3050 of 10000 in total
  1. Indication

    Hemorrhagic disease of the newborn

    go.drugbank.com/conditions/DBCOND0022633
    Drugs: Phylloquinone
    Synonyms: Hemorrhagic disease of the newborn due to vitamin K deficiency (disorder)
  2. Drug

    Irofulven

    go.drugbank.com/drugs/DB05786
    Investigational

    MGI-114 (Irofulven) is currently being developed by MGI PHARMA, Inc., an emerging oncology-focused pharmaceutical company based in Minneapolis. … A novel anti-cancer compound synthesized by scientists at the University of California, San Diego more than a decade ago from toxins of the poisonous jack-o-lantern mushroom, has been granted “fast track

  3. Drug

    Rindopepimut

    go.drugbank.com/drugs/DB05374
    Investigational

    Rindopepimut (CDX-110) is an injectable peptide cancer vaccine which targets a mutant protein called EGFRvIII present in about 25% to 30% of glioblastoma cases. … The vaccine consists of the EGFRv3-specific peptide (a 13-amino acid mutant vIII epitope) conjugated to the non-specific immunomodulator keyhole limpet hemocyanin (KLH).

  4. Drug

    Betamethasone phosphate

    go.drugbank.com/drugs/DB14669
    ApprovedVet approved

    Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible [betamethasone] to agonize glucocorticoid receptors.

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 Substrates
  5. Drug

    Methsuximide

    go.drugbank.com/drugs/DB05246
    Approved

    It is sold by Pfizer under the name Petinutin.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 Inhibitors
  6. Drug

    Donislecel

    go.drugbank.com/drugs/DB17961
    Approved

    [L47196] Overall, 21 patients achieved insulin independence for a year or more, with 11 patients not needing insulin for 1 to 5 years and 10 patients for more than 5 years. … , by not relying on exogenous and intentional insulin administration to control blood glucose.

  7. Drug

    Sulfadoxine

    go.drugbank.com/drugs/DB01299
    ApprovedInvestigationalWithdrawn

    A long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.

    Mixtures: SULFADOXINA 500 MG + PIRIMETAMINA 25 MG TABLETAS
  8. Drug

    Technetium Tc-99m disofenin

    go.drugbank.com/drugs/DB09164
    ApprovedWithdrawn

    It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary … However disofenin is the most commonly used iminodiacetic acid since it has a high liver to renal extraction and its hepatic uptake is not as highly dependent on serum bilirubin levels (a competitive inhibitor

    Synonyms: Technetium Tc 99m Disofenin, Technetium Tc-99m disofenin
  9. Target

    Nucleotide triphosphate diphosphatase NUDT15

    go.drugbank.com/bio_entities/BE0009809
    EnzymeHumans

    Therefore, the potential in vivo sanitizing role of this enzyme, that would consist in removing oxidatively damaged forms of nucleosides to prevent their incorporation into DNA, is unclear (PubMed:22556419 … Hydrolyzes oxidized nucleosides triphosphates like 8-oxo-dGTP in vitro, but the specificity and efficiency towards these substrates are low.

    Synonyms: Nucleoside diphosphate-linked to another moiety X hydrolase 15
  10. Indication

    Burns first degree

    go.drugbank.com/conditions/DBCOND0015343
    Drugs: Centella asiatica · Nepidermin · Pheniramine · St. John's Wort · Zinc oxide
    Synonyms: Erythema due to burn (first degree), unspecified site