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Phenprocoumon
go.drugbank.com/drugs/DB00946ApprovedInvestigationalWithdrawnCoumarin derivative that acts as a long-acting oral anticoagulant.
Synonyms: 3-(1-Phenylpropyl)-4-hydroxycoumarin, 3-(1'-Phenyl-propyl)-4-oxycoumarinCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesDifluprednate
go.drugbank.com/drugs/DB06781ApprovedInvestigationalDifluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated with ocular surgery. It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Otec % 0,05 Göz Damlası, Emülsiyon (5 mL), DİFLUNAT POMAT, 20 GBelatacept
go.drugbank.com/drugs/DB06681ApprovedInvestigationalFDA approved on June 15, 2011. … Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each.
Categories: Selective T Cell Costimulation Blocker, T Lymphocyte Costimulation Activity BlockadeProducts: NULOJIX ®250 MG/ VIAL POLVO LIOFILIZADO PARA SOLUCION INYECTABLE INTRAVENOSAPivampicillin
go.drugbank.com/drugs/DB01604ApprovedWithdrawnPivalate ester analog of ampicillin.
Categories: Penicillin G, Heterocyclic Compounds, 2-RingProducts: PIVACIL KAPSUL 350 MG, 1000 ADET, PIVACIL KAPSUL 350 MG, 500 ADETRetinol dehydrogenase 5
go.drugbank.com/bio_entities/BE0000570TargetEnzymeHumansCatalyzes the oxidation of cis-isomers of retinol, including 11-cis-, 9-cis-, and 13-cis-retinol in an NAD-dependent manner (PubMed:10588954, PubMed:11675386, PubMed:9115228, PubMed:9931293). Has no activity towards all-trans retinal (By...
Polypeptides: Retinol dehydrogenase 5Synonyms: Short chain dehydrogenase/reductase family 9C member 5Peroxiredoxin-5, mitochondrial
go.drugbank.com/bio_entities/BE0000907TargetEnzymeHumansThiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor o...
Polypeptides: Peroxiredoxin-5, mitochondrialSynonyms: Thioredoxin-dependent peroxiredoxin 55-aminolevulinate synthase
go.drugbank.com/bio_entities/BE0002158TargetHumansCatalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products.
Polypeptides: 5-aminolevulinate synthaseSynonyms: 5-aminolevulinic acid synthaseIntegrin alpha-5
go.drugbank.com/bio_entities/BE0008988TargetHumansIntegrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands.
Polypeptides: Integrin alpha-5Synonyms: VLA-5Thyroxine 5-deiodinase
go.drugbank.com/bio_entities/BE0009333TargetEnzymeHumansT1), rT3 to 3',5'-diiodothyronine (3',5'-T2) and 3,3'-T2 to 3'-monoiodothyronine (3'-T1) via inner-ring deiodination (IRD) (PubMed:7593630, PubMed:12586771, PubMed:12746313, PubMed:18821722, PubMed:18339710 … Catalyzes the deiodination of L-thyroxine (T4) to 3,3',5'-triiodothyronine (rT3), 3,5,3'-triiodothyronine (T3) to 3,3'-diiodothyronine (3,3'-T2), 3,5-diiodothyronine (3,5-T2) to 3-monoiodothyronine (3-
Polypeptides: Thyroxine 5-deiodinaseFunction: thyroxine 5'-deiodinase activityPseudouridine-5'-phosphatase
go.drugbank.com/bio_entities/BE0014361EnzymeHumansDephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine
Polypeptides: Pseudouridine-5'-phosphataseSynonyms: 5'-PsiMPase, Pseudouridine-5'-monophosphatase