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Displaying results 3431 - 3440 of 10000 in total
  1. Drug

    Ornidazole

    go.drugbank.com/drugs/DB13026
    Investigational

    Ornidazole has been used in trials studying the prevention of Elective Colorectal Surgery.

    Mixtures: ORNISASIN 500 MG/500 MG FILM TABLET, 10 ADET, ORNISASIN 500 MG/500 MG FILM TABLET, 20 ADETCategories: Heterocyclic Compounds, 1-Ring
  2. Pathway

    Acylcarnitine 5-Hydroxydec-5-enoylcarnitine

    smpdb.ca/view/SMP0123869
    Metabolic

    5-Hydroxydec-5-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxydec-5-enoyl-CoA reacts with L-carnitine to form 5-hydroxydec-5-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  3. Drug

    Lorlatinib

    go.drugbank.com/drugs/DB12130
    ApprovedInvestigational

    include lorlatinib as a first-line treatment option in advanced ALK-positive NSCLC. … Lorlatinib is a third-generation ALK tyrosine kinase inhibitor (TKI) for patients with ALK-positive metastatic non-small cell lung cancer[L39905] which was first approved by the US FDA in November of 2018

    Categories: MATE 1 Inhibitors, P-glycoprotein inducersProducts: LORBRENA® 25 MG, LORBRENA® 100 MG
  4. Drug

    Coal tar

    go.drugbank.com/drugs/DB11082
    Approved

    Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas.

    Mixtures: PREPARED COAL TAR 5% ET SALICYLIC ACID 2% OINTMENT, Multi-action Denorex 2-IN-1 Dandruff Shampoo + ConditionerProducts: COAL TAR SOLUTION 5% IN AQUEOUS CREAM, Estar Gel 5%
  5. Drug

    Aprepitant

    go.drugbank.com/drugs/DB00673
    ApprovedInvestigational

    Aprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting … Aprepitant has little or no affinity for serotonin (5-HT3), dopamine, and corticosteroid receptors, the targets of existing therapies for chemotherapy-induced nausea and vomiting (CI NV).

    Mixtures: EMEND® 80 MG/125 MG, EMEND® 80 MG/125 MGCategories: Substance P/Neurokinin-1 Receptor Antagonist, Neurokinin 1 Antagonists
  6. Drug

    Stavudine

    go.drugbank.com/drugs/DB00649
    ApprovedInvestigational

    A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.

    Synonyms: 2',3'-Didehydro-3'-deoxythimidine, 1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymineMixtures: TRIVIRO LNS® LAMIVUDINA 150 MG NEVIRAPINA 200 MG ESTAVUDINA 40 MG, CIPLABUDINA ES 30
  7. Drug

    Etonogestrel

    go.drugbank.com/drugs/DB00294
    ApprovedInvestigational

    Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. … [A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]

    Mixtures: EXELRING ®, Perlinring 0,120 mg/0,015 mg pro 24 Stunden - VaginalringCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  8. Drug

    Bedaquiline

    go.drugbank.com/drugs/DB08903
    ApprovedInvestigational

    [A261856] Currently, bedaquiline is the last-line anti-TB drug and must only be used in an appropriate combination regimen.[L48506,A261866] … Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline.

    Synonyms: 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-olCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Pathway

    Acylcarnitine 5-Hydroxydec-5-enedioylcarnitine

    smpdb.ca/view/SMP0123883
    Metabolic

    5-Hydroxydec-5-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxydec-5-enedioyl-CoA reacts with L-carnitine to form 5-hydroxydec-5-enedioylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  10. Drug

    Diethylpropion

    go.drugbank.com/drugs/DB00937
    ApprovedIllicitInvestigational

    A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category.

    Synonyms: 1-phenyl-2-diethylamino-1-propanone, 2-(diethylamino)-1-phenyl-1-propanoneProducts: NEOBES 50, Diethylpropion Hydrochloride ER