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Displaying results 3641 - 3650 of 10000 in total
  1. Target

    Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

    go.drugbank.com/bio_entities/BE0001205
    TargetHumans

    Catalyzes the cleavage of 2'-deoxyuridine 5'-triphosphate (dUTP) into 2'-deoxyuridine 5'-monophosphate (dUMP) and inorganic pyrophosphate and through its action efficiently prevents uracil misincorporation

    Polypeptides: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
  2. Target

    Fatty acid-binding protein 5

    go.drugbank.com/bio_entities/BE0001984
    CarrierTargetHumans

    Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specifi...

    Polypeptides: Fatty acid-binding protein 5
  3. Target

    5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

    go.drugbank.com/bio_entities/BE0002007
    TargetEscherichia coli (strain K12)

    Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. … Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose

    Polypeptides: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidaseSynonyms: 5'-deoxyadenosine nucleosidase, 5'-methylthioadenosine nucleosidase
  4. Target

    Proteasome subunit beta type-5

    go.drugbank.com/bio_entities/BE0002348
    TargetHumans

    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associat...

    Polypeptides: Proteasome subunit beta type-5Synonyms: beta-5, Proteasome subunit beta-5
  5. Target

    Arachidonate 5-lipoxygenase-activating protein

    go.drugbank.com/bio_entities/BE0002382
    TargetHumans

    Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5.

    Polypeptides: Arachidonate 5-lipoxygenase-activating protein
  6. Target

    5-methyltetrahydrofolate--homocysteine S-methyltransferase

    go.drugbank.com/bio_entities/BE0002812
    TargetMoorella thermoacetica (strain ATCC 39073)

    Polypeptides: 5-methyltetrahydrofolate--homocysteine S-methyltransferase
  7. Target

    Ribose-5-phosphate isomerase B

    go.drugbank.com/bio_entities/BE0002944
    TargetMycobacterium tuberculosis

    Catalyzes the interconversion of ribulose-5-P and ribose-5-P. It has not isomerase activity towards D-allose 6-phosphate.

    Polypeptides: Ribose-5-phosphate isomerase BFunction: ribose-5-phosphate isomerase activity
  8. Target

    2'-5'-oligoadenylate synthase 1

    go.drugbank.com/bio_entities/BE0004585
    TargetHumans

    Can generate high levels of 2',5'-oligoadenylates in transformed cells, targeting them to innate and adaptive immunesurveillance mechanisms (PubMed:40010341). … Catalyzes the formation of 2'-5'-oligoadenylates (2-5A) from polymerization of ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent

    Polypeptides: 2'-5'-oligoadenylate synthase 1Synonyms: (2-5')oligo(A) synthase 1
  9. Target

    Pyrroline-5-carboxylate reductase 3

    go.drugbank.com/bio_entities/BE0004615
    TargetHumans

    Proline is synthesized from either glutamate or ornithine; both are converted to P5C, and then to proline via pyrroline-5-carboxylate reductases (PYCRs) (PubMed:23024808). … Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate (P5C) to L-proline using NAD(P)H (PubMed:23024808, PubMed:36414121).

    Polypeptides: Pyrroline-5-carboxylate reductase 3Synonyms: Pyrroline-5-carboxylate reductase-like protein
  10. Target

    DAN domain family member 5

    go.drugbank.com/bio_entities/BE0005538
    TargetHumans

    Antagonist of the extracellular signaling protein NODAL, which is required for correct left-right patterning during embryonic development (By similarity). Antagonist of BMP and TGF-beta signaling (PubMed:33587337). Independently of its r...

    Polypeptides: DAN domain family member 5