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Displaying results 3681 - 3690 of 10000 in total
  1. Drug

    Squalene

    go.drugbank.com/drugs/DB11460
    ApprovedInvestigationalVet approvedWithdrawn

    It is a natural 30-carbon isoprenoid compound and intermediate metabolite in the synthesis of cholesterol. It is not susceptible to lipid peroxidation and provides skin protection. … It is ubiquitously distributed in human tissues where it is transported in serum generally in association with very low density lipoproteins. Squalene is investigated as an adjunctive cancer therapy.

    Mixtures: K-OMEGASQUA (Softgel)Synonyms: (E,E,E,E)-Squalene, (all-E)-2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene
  2. Drug

    Aluminum chlorohydrate

    go.drugbank.com/drugs/DB11573
    Approved

    Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. … It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent.

    Mixtures: PERS-MANT %19 + %2 JEL (30 G), KURSEPT %19 + %1 KREM (30 G)Products: TERKUR %19 KREM (30 G), Arrid Ext Dry Unscent Spray Aer 10%
  3. Drug

    Copper gluconate

    go.drugbank.com/drugs/DB11246
    ApprovedInvestigational

    According to the good manufacturing or feeding practice by the FDA, copper gluconate is used as a nutrient or dietary supplement and is generally recognized as safe for use at a level not exceeding 0.005 … Copper gluconate is a copper salt of D-gluconic acid that displays a light blue to bluish-green color.

    Mixtures: Vitamin A C E W.niacinam.beta Car.and Min., Super Daily No 2Products: Copper (gluconate) 2 Mg Tablets
  4. Drug

    Human Rho(D) immune globulin

    go.drugbank.com/drugs/DB11597
    Approved

    It was approved by FDA as treatment for suppression of rhesus (Rh) isoimmunization or chronic immune thrombocytopenic purpura (ITP) in adults. … Rho (D) immune globulin is available as a sterile, lyophilized or liquid gamma globulin (IgG) fraction containing antibodies to the Rh0 (D) antigen (D antigen) under the name Rhophylac (IM/IV).

    Categories: Human Immunoglobulin G, anti-D (rh) immunoglobulinSynonyms: IGG, Rho (D), Anti-D immunoglobulin
  5. Drug

    Tolbutamide

    go.drugbank.com/drugs/DB01124
    Approved

    It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin … Tolbutamide and its metabolites are excreted in urine (75-85%) and feces.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C18 SubstratesSynonyms: 1-Butyl-3-tosylurea, 1-Butyl-3-(p-tolylsulfonyl)urea
  6. Drug

    Camphor

    go.drugbank.com/drugs/DB01744
    ApprovedInvestigationalWithdrawn

    The FDA ruled that camphorated oil could not be marketed in the United States and that no product could contain a concentration higher than 11%. … Camphor is a bicyclic monoterpene ketone found widely in plants, especially _Cinnamomum camphora_. It is used topically as a skin antipruritic and as an anti-infective agent.

    Mixtures: VİCKS İNHALER 415,4 MG + 415,4 MG/1 G BURUN ÇUBUĞU, OTACI TERMAL POMAD, 50 GSynonyms: (+)-bornan-2-one, (1R,4R)-camphor
  7. Target

    Sodium channel protein type 10 subunit alpha

    go.drugbank.com/bio_entities/BE0000177
    TargetHumans

    Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sod...

    Polypeptides: Sodium channel protein type 10 subunit alpha
  8. Target

    ATP-sensitive inward rectifier potassium channel 10

    go.drugbank.com/bio_entities/BE0009591
    TargetHumans

    May be responsible for potassium buffering action of glial cells in the brain (By similarity). Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it (Pu...

    Polypeptides: ATP-sensitive inward rectifier potassium channel 10Synonyms: Potassium channel, inwardly rectifying subfamily J member 10
  9. Target

    Mitogen-activated protein kinase kinase kinase 10

    go.drugbank.com/bio_entities/BE0009462
    TargetHumans

    Activates the JUN N-terminal pathway

    Polypeptides: Mitogen-activated protein kinase kinase kinase 10
  10. Target

    Tumor necrosis factor ligand superfamily member 10

    go.drugbank.com/bio_entities/BE0010497
    TargetHumans

    Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG (PubMed:10549288, PubMed:26457518). Induces apoptosis. Its activity may be modulated by binding to the d...

    Polypeptides: Tumor necrosis factor ligand superfamily member 10