Search
Fedratinib
go.drugbank.com/drugs/DB12500ApprovedInvestigational[A183176,L8090] It is an anilinopyrimidine derivative.[A183188] Fedratinib was granted FDA approval on August 16, 2019.[L8090] … Fedratinib, also known as SAR302503 and TG101348, is a tyrosine kinase inhibitor used to treat intermediate-2 and high risk primary and secondary myelofibrosis.
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsProducts: Inrebic 100 mg capsules, Inrebic 100 mg Sert Kapsül, 120 ADETAlteplase
go.drugbank.com/drugs/DB00009ApprovedInvestigationalAlteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent.[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. … [A252330,L43125] Alteplase is a purified glycoprotein of 527 amino acids expressed in Chinese hamster ovary (CHO) cells.
Synonyms: t-PA, r-tPAProducts: ACTILYSE 50 MG FLAKON, 1 ADET, ACTILYSE TREATMENT-SET 50 mg/vialAzelaic acid
go.drugbank.com/drugs/DB00548ApprovedInvestigationalAzelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. … Azelaic acid is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%.
Synonyms: n-nonanedioic acidMixtures: Azelaic Acid 15% / Niacinamide 4%, 2% Salicylic Acid FACIAL CLEANSERRoxithromycin
go.drugbank.com/drugs/DB00778ApprovedInvestigationalWithdrawnIt is marketed in Australia as a treatment for respiratory tract, urinary and soft tissue infections. … Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to [erythromycin], [azithromycin], or [clarithromycin].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsSynonyms: (9E)-erythromycin 9-(O-((2-methoxyethoxy)methyl)oxime)Polyvinyl alcohol
go.drugbank.com/drugs/DB11060ApprovedPolyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes [L2826]. … Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol.
Mixtures: SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 ML, FULLFRESH 5,60 MG/2,40 MG TEK DOZLUK GÖZ DAMLASI, ÇÖZELTİCategories: Compounds used in a research, industrial, or household settingNaftidrofuryl
go.drugbank.com/drugs/DB13588ApprovedCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: PRAXILENE TABLET 200 mg, Dusodril retard 100 mg - FilmtablettenProtionamide
go.drugbank.com/drugs/DB12667ApprovedInvestigationalWithdrawnProthionamide has been used in trials studying the treatment of MDR-TB and HIV Infections.
Categories: Heterocyclic Compounds, 1-RingProducts: TIONAMID 250 MG DRAJE, 50 ADET, TIONAMID 250 MG DRAJE, 500 ADETSafinamide
go.drugbank.com/drugs/DB06654ApprovedInvestigationalIt was approved in Europe in February 2015, and in the United States on March 21, 2017.
Categories: Cytochrome P-450 Substrates, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: Equfina Film coated Tablets 50 mg, XADAGO 50 MG TABLETAS RECUBIERTAS CON PELÍCULAAcylcarnitine (5R)-5-hydroxyhexanoylcarnitine
smpdb.ca/view/SMP0123336Metabolic(5R)-5-hydroxyhexanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (5R)-5-hydroxyhexanoyl-CoA reacts with L-carnitine to form (5R)-5-hydroxyhexanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Acylcarnitine Dec-5-enedioylcarnitine
smpdb.ca/view/SMP0123875MetabolicDec-5-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, dec-5-enedioyl-CoA reacts with L-carnitine to form dec-5-enedioylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5