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Displaying results 3791 - 3800 of 10000 in total
  1. Target

    T cell receptor beta variable 5-6

    go.drugbank.com/bio_entities/BE0023691
    TargetHumans

    V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and ...

    Polypeptides: T cell receptor beta variable 5-6
  2. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

    go.drugbank.com/bio_entities/BE0000089
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The ...

    Polypeptides: NADH dehydrogenase [ubiquinone] iron-sulfur protein 5
  3. Target

    Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

    go.drugbank.com/bio_entities/BE0000244
    TargetHumans

    Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate.

    Polypeptides: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
  4. Target

    cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A

    go.drugbank.com/bio_entities/BE0000436
    TargetHumans

    Cyclic nucleotide phosphodiesterase with specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PubMed:1315035, PubMed:25961942, PubMed:8155697, PubMed:8695850). Also has ...

    Polypeptides: cGMP-inhibited 3',5'-cyclic phosphodiesterase 3AFunction: 3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity
  5. Target

    Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1

    go.drugbank.com/bio_entities/BE0003094
    TargetHumans

    The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate

    Polypeptides: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1
  6. Target

    POU domain, class 5, transcription factor 1

    go.drugbank.com/bio_entities/BE0003665
    TransporterTargetHumans

    Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3').

    Polypeptides: POU domain, class 5, transcription factor 1
  7. Target

    2,3-diketo-5-methylthiopentyl-1-phosphate enolase

    go.drugbank.com/bio_entities/BE0003741
    TargetGeobacillus kaustophilus (strain HTA426)

    Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).

    Polypeptides: 2,3-diketo-5-methylthiopentyl-1-phosphate enolaseFunction: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity
  8. Target

    Type II inositol 1,4,5-trisphosphate 5-phosphatase

    go.drugbank.com/bio_entities/BE0004437
    TargetHumans

    Also hydrolyzes the 5-position phosphate from inositol 1,4,5-trisphosphate (Ins(1,4,5)P3), thereby modulating cellular signaling events … Regulates phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) cellular levels by cleaving the phosphate at the 5-position producing PtdIns(4)P.

    Polypeptides: Type II inositol 1,4,5-trisphosphate 5-phosphataseSynonyms: Phosphoinositide 5-phosphatase, 75 kDa inositol polyphosphate-5-phosphatase
  9. Target

    Insulin-like growth factor-binding protein 5

    go.drugbank.com/bio_entities/BE0009661
    CarrierHumans

    Multifunctional protein that plays a critical role in regulating the availability of IGFs to their receptors and thereby regulates IGF-mediated cellular processes including proliferation, differentiation, and apoptosis in a cell-type spe...

    Polypeptides: Insulin-like growth factor-binding protein 5Synonyms: IBP-5, IGFBP-5
  10. Drug

    Zotepine

    go.drugbank.com/drugs/DB09225
    ApprovedWithdrawn

    Zotepine, with the formula (2-chloro-11-(2-dimethyl-amino-ethoxy)-dibenzo thiepin, is a neuroleptic drug. It was designed and synthesized by Fujisawa Pharmaceutical Co Ltd. … [A31855] It has been used as an antipsychotic in Japan, India and some places in Europe like UK and Germany since 1980's.[A31857] Zotepine was never approved by the FDA.

    Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: ZOLEPTIL © 50 MG TABLETAS RECUBIERTAS.