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Displaying results 3791 - 3800 of 10000 in total
  1. Drug

    Neratinib

    go.drugbank.com/drugs/DB11828
    ApprovedInvestigational

    Neratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer.

    Synonyms: 奈拉替尼Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 Substrates
  2. Drug

    Choriogonadotropin alfa

    go.drugbank.com/drugs/DB00097
    ApprovedInvestigational

    -13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). … Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN

    Products: OVITRELLE 250 MCG/0,5 ML KULLANIMA HAZIR ŞIRINGADA ENJEKSİYONLUK ÇÖZELTİ, 1 ADET, Ovidrel Solution for Injection 250 mcg
  3. Drug

    Oxidronic acid

    go.drugbank.com/drugs/DB14159
    Approved

    Synonyms: HMD-PProducts: TECHNESCAN HDP FOR INJECTION 3 mg/vial, TECHNESCAN HDP POWDER FOR INJECTION 3.15 mg/vial
  4. Drug

    Dalbavancin

    go.drugbank.com/drugs/DB06219
    ApprovedInvestigational

    pyogenes, S. agalactiae, S. dysgalactiae, the S. anginosus group (including S. anginosus, S. intermedius, and S. constellatus), and Enterococcus faecalis (vancomycin susceptible strains) [FDA Label, F2356 … Dalbavancin acts by interfering with bacterial cell wall synthesis by binding to the D-alanyl-D-alanine terminus of nascent cell wall peptidoglycan and preventing cross-linking [FDA Label, F2356, A4072

    Products: Dalbavancin Accord 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, Dalbavancin ratiopharm 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  5. Drug

    Poa pratensis pollen

    go.drugbank.com/drugs/DB10366
    Approved

    Poa pratensis pollen is the pollen of the Poa pratensis plant. Poa pratensis pollen is mainly used in allergenic testing.

    Mixtures: Oralair 100 IR, ORALAIR 100 IR + 300 IR SublingualtablettenProducts: Standardized Grass Pollen - Kentucky Bluegrass (100 Bau/ml), Standardized Grass Pollen - Kentucky Bluegrass (100000 Bau/ml)
  6. Target

    Sodium channel protein type 5 subunit alpha

    go.drugbank.com/bio_entities/BE0000197
    TargetHumans

    Pore-forming subunit of Nav1.5, a voltage-gated sodium (Nav) channel that directly mediates the depolarizing phase of action potentials in excitable membranes (PubMed:33712541, PubMed:40768348). Navs, also called VGSCs (voltage-gated sod...

    Polypeptides: Sodium channel protein type 5 subunit alpha
  7. Target

    Tumor necrosis factor receptor superfamily member 5

    go.drugbank.com/bio_entities/BE0001196
    TargetHumans

    Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity)

    Polypeptides: Tumor necrosis factor receptor superfamily member 5
  8. Target

    cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

    go.drugbank.com/bio_entities/BE0001223
    TargetHumans

    Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological process (PubMed:14592490, PubMed:21393242). Regulates angiogenesis by inhibitin...

    Polypeptides: cGMP-inhibited 3',5'-cyclic phosphodiesterase 3BFunction: 3',5'-cyclic-AMP phosphodiesterase activity
  9. Target

    Intracellular exo-alpha-(1->5)-L-arabinofuranosidase

    go.drugbank.com/bio_entities/BE0001766
    TargetGeobacillus stearothermophilus

    Catalyzes the cleavage of terminal alpha-(1->5)-arabinofuranosyl bonds in different hemicellulosic homopolysaccharides (branched and debranched arabinans).

    Polypeptides: Intracellular exo-alpha-(1->5)-L-arabinofuranosidaseSynonyms: Intracellular arabinan exo-alpha-(1->5)-L-arabinosidase
  10. Target

    NAD-dependent protein deacylase sirtuin-5, mitochondrial

    go.drugbank.com/bio_entities/BE0003362
    TargetHumans

    NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins (PubMed:21908771, PubMed:22076378, PubMed:24703693, PubMed:29180469). Activates CPS1 an...

    Polypeptides: NAD-dependent protein deacylase sirtuin-5, mitochondrialSynonyms: SIR2-like protein 5, Regulatory protein SIR2 homolog 5