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Displaying results 3811 - 3820 of 10000 in total
  1. Drug

    Mitotane

    go.drugbank.com/drugs/DB00648
    ApprovedInvestigational

    It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma[A263010] and is used off-label for the management of Cushing's syndrome.[A263016] … Mitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InducersSynonyms: 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-benzene, o,p'-DDD
  2. Indication

    Palmoplantar keratoderma

    go.drugbank.com/conditions/DBCOND0020029
    Drugs: Salicylic acid
    Synonyms: Keratosis Palmaris et Plantaris, Keratoderma palmaris et plantaris
  3. Drug

    Tocainide

    go.drugbank.com/drugs/DB01056
    ApprovedWithdrawn

    An antiarrhythmic agent which exerts a potential- and frequency-dependent block of sodium channels.

    Categories: Antiarrhythmics, Class I, Cytochrome P-450 SubstratesSynonyms: 2-Amino-2',6'-propionoxylidide, 2-amino-N-(2,6-dimethylphenyl)propanamide
  4. Drug

    Clobetasol propionate

    go.drugbank.com/drugs/DB01013
    ApprovedInvestigational

    [A190936] Clobetasol Propionate was granted FDA approval on 27 December 1985.[L11809] … Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors.

    Synonyms: 21-chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionate, Clobetasol propionate EInternational brands: Embeline E
  5. Pathway

    Acylcarnitine 10-(3,4-dimethyl-5-propylfuran-2-yl)decanoylcarnitine

    smpdb.ca/view/SMP0123491
    Metabolic

    10-(3,4-dimethyl-5-propylfuran-2-yl)decanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 10-(3,4-dimethyl-5-propylfuran-2-yl)decanoyl-CoA reacts with L-carnitine to form 10-(3,4-dimethyl-5-propylfuran-2-yl)decanoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  6. Pathway

    Acylcarnitine 10-(3,4-dimethyl-5-pentylfuran-2-yl)decanoylcarnitine

    smpdb.ca/view/SMP0123492
    Metabolic

    10-(3,4-dimethyl-5-pentylfuran-2-yl)decanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 10-(3,4-dimethyl-5-pentylfuran-2-yl)decanoyl-CoA reacts with L-carnitine to form 10-(3,4-dimethyl-5-pentylfuran-2-yl)decanoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  7. Drug

    Emedastine

    go.drugbank.com/drugs/DB01084
    Approved

    Emedastine is an antihistamine used in eye drops to treat allergic conjunctivitis.

    Synonyms: 1-(2-Ethoxy-ethyl)-2-(4-methyl-[1,4]diazepan-1-yl)-1H-benzoimidazole, 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzimidazoleCategories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Tetanus immune globulin, human

    go.drugbank.com/drugs/DB11604
    ApprovedInvestigational

    It contains antibodies against tetanus toxoid and is primarily used as prophylaxis against tetanus in wounded patients.

    Products: TETANUS GAMMA KEDRION ® 250 UI/1 ML, TETAGAM P 250 IU/1 ML IM KULLANIMA HAZIR ENJEKTÖRDE ENJEKSİYONLUK ÇÖZELTİ
  9. Drug

    Isopropyl alcohol

    go.drugbank.com/drugs/DB02325
    ApprovedInvestigational

    An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.

    Mixtures: ChloraPrep 20 mg/ml + 0,7 ml/ml Lösung zur Anwendung auf der Haut, ChloraPrep gefärbt 20 mg/ml + 0,7 ml/ml Lösung zur Anwendung auf der HautCategories: Compounds used in a research, industrial, or household setting
  10. Drug

    Carbopol 974P

    go.drugbank.com/drugs/DB05384
    ApprovedWithdrawn

    It was under development by ReProtect LLC. It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies. … Carbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with a broad-spectrum mechanism based on acidification of pathogens.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Carbomer 974 (P), Carbomer homopolymer type B