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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
go.drugbank.com/bio_entities/BE0000243TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The ...
Polypeptides: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial5'-AMP-activated protein kinase catalytic subunit alpha-1
go.drugbank.com/bio_entities/BE0000677TargetHumansCatalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PubMed:17307971, PubMed:17712357, PubMed:24563466, PubMed:31492851, PubMed:37821951...
Polypeptides: 5'-AMP-activated protein kinase catalytic subunit alpha-1tRNA (cytidine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase
go.drugbank.com/bio_entities/BE0002518TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
Polypeptides: tRNA (cytidine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferaseHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
go.drugbank.com/bio_entities/BE0003134TargetHumansSpecifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity...
Polypeptides: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AFunction: 3',5'-cyclic-AMP phosphodiesterase activityLeucine-rich repeat-containing G protein-coupled receptor 5
go.drugbank.com/bio_entities/BE0010835TargetHumansReceptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with ph...
Polypeptides: Leucine-rich repeat-containing G protein-coupled receptor 5Transient receptor potential cation channel subfamily M member 5
go.drugbank.com/bio_entities/BE0020643TargetHumansMonovalent cation-selective ion channel activated by intracellular Ca(2+) in a voltage- and temperature-dependent manner (PubMed:14634208). Mediates the transport of Na(+), K(+) and Cs(+) ions equally well (PubMed:14634208). Activated di...
Polypeptides: Transient receptor potential cation channel subfamily M member 5Synonyms: LTrpC-5, Long transient receptor potential channel 5Procainamide
go.drugbank.com/drugs/DB01035ApprovedA derivative of procaine with less CNS action.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSynonyms: p-Amino-N-(2-diethylaminoethyl)benzamide, p-Aminobenzoic diethylaminoethylamidePropylene glycol
go.drugbank.com/drugs/DB01839ApprovedInvestigationalA clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Mixtures: SYSTANE LUBRIKANT % 0,4 + %0,3 GÖZ DAMLASI, ÇÖZELTI, 15 ML, SKINOREN %20 KREM, 30 GCategories: Compounds used in a research, industrial, or household settingTransient receptor potential cation channel subfamily V member 5
go.drugbank.com/bio_entities/BE0005112TransporterHumansConstitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine (PubMed:11549322, PubMed:18768590). Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubu...
Polypeptides: Transient receptor potential cation channel subfamily V member 5Solute carrier family 2, facilitated glucose transporter member 5
go.drugbank.com/bio_entities/BE0005216TransporterHumansFunctions as a fructose transporter that has only low activity with other monosaccharides (PubMed:16186102, PubMed:17710649, PubMed:28083649, PubMed:29548810, PubMed:8333543). Can mediate the uptake of 2-deoxyglucose, but with low effici...
Polypeptides: Solute carrier family 2, facilitated glucose transporter member 5Synonyms: GLUT-5, Glucose transporter type 5, small intestine