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Boceprevir
go.drugbank.com/drugs/DB08873ApprovedWithdrawnBoceprevir is an inhibitor of NS3/4A, a serine protease enzyme, encoded by HCV genotypes 1 and 4 [synthesis]. … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients [L852].
Categories: Amino Acids, Peptides, and Proteins, P-glycoprotein inhibitorsProducts: VICTRELIS ® CAPSULAS 200 MG (MOLECULA PROTEGIDA)Phenol
go.drugbank.com/drugs/DB03255ApprovedInvestigationalPhenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. … During the second world war, phenol injections were used as a means of execution by the Nazis. Phenol is a toxic compound whose vapours are corrosive to the skin, eyes, and respiratory tract.
Mixtures: DİŞİNOL 2 G + 0,5 G + 3,5 G/10 ML ÇÖZELTİ, COOLING 5 PLUSCategories: Compounds used in a research, industrial, or household setting, Phenol and DerivativesTolbutamide
go.drugbank.com/drugs/DB01124ApprovedTolbutamide and its metabolites are excreted in urine (75-85%) and feces. … It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin
Synonyms: 1-Butyl-3-tosylurea, 1-Butyl-3-(p-tolylsulfonyl)ureaCategories: Alimentary Tract and Metabolism, Genito Urinary System and Sex HormonesFlunitrazepam
go.drugbank.com/drugs/DB01544ApprovedIllicitSome reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug. … Flunitrazepam is a benzodiazepine with pharmacologic actions similar to those of diazepam that can cause anterograde amnesia.
Categories: Hypnotics and Sedatives, Benzodiazepine hypnotics and sedativesProducts: Rohypnol 1 mg - Filmtabletten, ROHYPNOL ROCHE TABLETAS 1 MGDelamanid
go.drugbank.com/drugs/DB11637ApprovedInvestigationalSpontaneous resistance to delamanid was observed during treatment, where mutation in one of the 5 F420 coenzymes responsible for bioactivation of delamanid contributes to this effect [L1407]. … It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen.
Synonyms: (R)-2-methyl-6-nitro-2-{4-[4-(4-trifluoromethoxyphenoxy)piperidin-1-yl]phenoxymethyl}-2,3-dihydroimidazo[2,1-b]oxazole, (2R)-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-2,3-dihydroimidazo(2,1-B)(1,3)oxazoleCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesCarbon dioxide
go.drugbank.com/drugs/DB09157ApprovedInvestigationalVet approvedduring bodily investigations, to inflate body cavities during surgery (such as key-hole surgery), and in solid form (dry ice) for freezing of tissue and removal of warts. … Medical Carbon Dioxide is a liquefied medicinal gas, supplied in cylinders filled to a high pressure. Medical Carbon Dioxide may be used in different situations, e.g.
Mixtures: Carbon Dioxide 1% W Air, Carbon Dioxide 1% W OxygenCategories: X-Ray Contrast ActivityGilteritinib
go.drugbank.com/drugs/DB12141ApprovedInvestigationalThis drug was approved after being designed as an orphan drug with a fast track and priority review status.[L4830] … Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group.
Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingProducts: XOSPATA 40 MG FİLM KAPLI TABLET, 84 ADET, XOSPATA® FILM-COATED TABLETS 40MGAcylcarnitine 10-Methyldodecanoylcarnitine
smpdb.ca/view/SMP0123613Metabolic10-Methyldodecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 10-methyldodecanoyl-CoA reacts with L-carnitine to form 10-methyldodecanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Acylcarnitine 10-Methylpentadecanoylcarnitine
smpdb.ca/view/SMP0123640Metabolic10-Methylpentadecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 10-methylpentadecanoyl-CoA reacts with L-carnitine to form 10-methylpentadecanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Acylcarnitine 10-MethylHexadecanoylcarnitine
smpdb.ca/view/SMP0123651Metabolic10-MethylHexadecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 10-methylhexadecanoyl-CoA reacts with L-carnitine to form 10-methylhexadecanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5