Search

Displaying results 3881 - 3890 of 10000 in total
  1. Drug

    Treprostinil

    go.drugbank.com/drugs/DB00374
    ApprovedInvestigational

    However, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room temperature. … [A248770,A248775] The use of more stable alternatives such as treprostinil provides patients with PAH with more treatment options.

  2. Drug

    Silicon dioxide

    go.drugbank.com/drugs/DB11132
    Approved

    It is found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite as transparent and tasteless crystals. … Colloidal silica is also used as a wine, beer, and juice fining agent or stabilizer.

    Mixtures: Dr.pauhls Natural Tone Up Tooth, DOCTRUST ONE S ToothCategories: Complex Mixtures
  3. Drug

    Ornidazole

    go.drugbank.com/drugs/DB13026
    Investigational

    Ornidazole has been used in trials studying the prevention of Elective Colorectal Surgery.

    Categories: Genito Urinary System and Sex Hormones, Antibacterials for Systemic Use
  4. Drug

    Aldosterone

    go.drugbank.com/drugs/DB04630
    Investigational

    A hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.

    Categories: Sex Hormones and Insulins, Corticosteroids for Systemic Use
  5. Drug

    Temoporfin

    go.drugbank.com/drugs/DB11630
    Approved

    It is currently available under the brand name Foscan. … Temoporfin is a photosensitizing agent used in the treatment of squamous cell carcinoma of the head and neck [FDA Label].

  6. Drug

    Denileukin diftitox

    go.drugbank.com/drugs/DB00004
    ApprovedInvestigational

    was originally approved by the FDA in 1999 for the treatment of cutaneous T-cell lymphoma (CTCL),[A264339, L51264] making it the first fusion protein cytotoxin approved to treat a human disease in the US … Denileukin diftitox is an IL2-receptor-directed cytotoxin, is a recombinant DNA-derived fusion protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met<sub>1</sub>-Thr<sub

  7. Drug

    Hexafluronium

    go.drugbank.com/drugs/DB00941
    Approved

    It is known to bind and block the activity of plasma cholinesterases. … Hexafluronium bromide is a neuromuscular blocking agent used in anesthesiology to prolong and potentiate the skeletal muscle relaxing action of suxamethonium during surgery.

  8. Drug

    Valoctocogene roxaparvovec

    go.drugbank.com/drugs/DB15561
    ApprovedInvestigationalWithdrawn

    [L43282,A252807] Valoctocogene roxaparvovec was approved by EMA in September 2022 and is indicated for the treatment of severe hemophilia A. It is not approved for use in the United States. … Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ).

    Categories: Complex Mixtures
  9. Drug

    Casdatifan

    go.drugbank.com/drugs/DB21701
    Investigational

    Casdatifan is a small molecule drug. The usage of the INN stem '-tifan' in the name indicates that Casdatifan is a hypoxia inducible factor (HIF)-2alpha (HIF-2a) inhibitor. … Casdatifan is under investigation in clinical trial NCT07000149 (A Study to Investigate the Efficacy and Safety of Volrustomig ± Casdatifan vs Nivolumab + Ipilimumab as 1L Treatment for Advanced ccRCC)

  10. Drug

    Cefotiam

    go.drugbank.com/drugs/DB00229
    Approved

    One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use