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Glutathione S-transferase kappa 1
go.drugbank.com/bio_entities/BE0000808TargetHumansGlutathione S-transferase that catalyzes the conjugation of glutathione to exogenous and endogenous compounds (PubMed:14709161, PubMed:14742434).
Polypeptides: Glutathione S-transferase kappa 1Synonyms: Glutathione S-transferase subunit 13S-methyl-5'-thioadenosine phosphorylase
go.drugbank.com/bio_entities/BE0001128TargetHumansCatalyzes the phosphorolytic cleavage of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose1-phosphate (PubMed:3091600, PubMed:8687427, PubMed:10404592). … Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine (PubMed:3091600, PubMed:8687427, PubMed:10404592).
Polypeptides: S-methyl-5'-thioadenosine phosphorylaseMicrosomal glutathione S-transferase 2
go.drugbank.com/bio_entities/BE0002290TargetEnzymeHumansCatalyzes several different glutathione-dependent reactions (PubMed:23409838, PubMed:26066610, PubMed:26656251, PubMed:8703034, PubMed:9278457). Catalyzes the glutathione-dependent reduction of lipid hydroperoxides, such as 5-HPETE (PubM...
Polypeptides: Microsomal glutathione S-transferase 2Synonyms: Microsomal glutathione S-transferase IIProtein-S-isoprenylcysteine O-methyltransferase
go.drugbank.com/bio_entities/BE0011941EnzymeHumansCatalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues
Polypeptides: Protein-S-isoprenylcysteine O-methyltransferaseFunction: protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activityGlutathione S-transferase omega-2
go.drugbank.com/bio_entities/BE0002291TargetHumansExhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monometh...
Polypeptides: Glutathione S-transferase omega-2Synonyms: Glutathione S-transferase omega 2-2Glutathione S-transferase Mu 4
go.drugbank.com/bio_entities/BE0000812TargetHumansCan also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator
Polypeptides: Glutathione S-transferase Mu 4Glutathione S-transferase 3, mitochondrial
go.drugbank.com/bio_entities/BE0002279TargetEnzymeHumansDisplays both glutathione S-transferase and glutathione peroxidase activities toward oxyeicosanoids, as part of cellular detoxification as well as synthesis of bioactive metabolites (PubMed:36370807, PubMed
Polypeptides: Glutathione S-transferase 3, mitochondrialBetaine--homocysteine S-methyltransferase 1
go.drugbank.com/bio_entities/BE0000845TargetHumansInvolved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline
Polypeptides: Betaine--homocysteine S-methyltransferase 1Function: betaine-homocysteine S-methyltransferase activityCreatine kinase S-type, mitochondrial
go.drugbank.com/bio_entities/BE0000410TargetHumansReversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such a...
Polypeptides: Creatine kinase S-type, mitochondrialSynonyms: S-MtCKG1/S-specific cyclin-D1
go.drugbank.com/bio_entities/BE0001027TargetHumansRegulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition
Polypeptides: G1/S-specific cyclin-D1