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Lovastatin Action Pathway (New)
smpdb.ca/view/SMP0124570Drug actionStatins are a class of medications that lower lipid levels and are administered to reduce illness and mortality in people who are at high risk of cardiovascular disease. … LDL-R localizes to the endoplasmic reticulum for transport and exocytosis to the cell surface.
Rosuvastatin
smpdb.ca/view/SMP0124577Drug actionStatins are a class of medications that lower lipid levels and are administered to reduce illness and mortality in people who are at high risk of cardiovascular disease. … LDL-R localizes to the endoplasmic reticulum for transport and exocytosis to the cell surface.
Simvastatin Action Pathway (New)
smpdb.ca/view/SMP0124578Drug actionStatins are a class of medications that lower lipid levels and are administered to reduce illness and mortality in people who are at high risk of cardiovascular disease. … LDL-R localizes to the endoplasmic reticulum for transport and exocytosis to the cell surface.
Fluvastatin Action Pathway (New)
smpdb.ca/view/SMP0124569Drug actionStatins are a class of medications that lower lipid levels and are administered to reduce illness and mortality in people who are at high risk of cardiovascular disease. … LDL-R localizes to the endoplasmic reticulum for transport and exocytosis to the cell surface.
Pravastatin Action Pathway (New)
smpdb.ca/view/SMP0124576Drug actionStatins are a class of medications that lower lipid levels and are administered to reduce illness and mortality in people who are at high risk of cardiovascular disease. … LDL-R localizes to the endoplasmic reticulum for transport and exocytosis to the cell surface.
Pitavastatin Action Pathway
smpdb.ca/view/SMP0126665Drug actionlipoprotein (LDL), and very low-density lipoprotein (VLDL). … Statin medication prescriptions can be given following any cardiovascular events and to people with a moderate risk of development of CVD.
Riboflavin Metabolism
smpdb.ca/view/SMP0000070MetabolicLike the other B vitamins, riboflavin is needed for the breaking down and processing of ketone bodies, lipids, carbohydrates, and proteins. … FAD and FMN are essential hydrogen carriers and are involved in over 100 redox reactions that take part in energy metabolism.
Arachidonic Acid Metabolism
smpdb.ca/view/SMP0000075Metabolic, inflammation, and hemostasis. … In resting cells arachidonic acid is present in the phospholipids (especially phosphatidylethanolamine and phosphatidylcholine) of membranes of the body’s cells, and is particularly abundant in the brain
Meloxicam Action Pathway
smpdb.ca/view/SMP0000106Drug actionThis in turn inhibits the calcium-dependent events, including PLA2 activation, involved in platelet activation and aggregation. … The increase in intracellular calcium activates kinases required for morphological change, transition to procoagulant surface, secretion of granular contents, activation of glycoproteins, and the activation
Ombitasvir Action Pathway
smpdb.ca/view/SMP0125941Drug actionThe lipoviroparticles attach to LDL-R and SR-B1, and then the virus binds to CD81 and subsequently claudin-1 and occludin, which mediate the late steps of viral entry. … The nucleocapsid protein core and the two envelope proteins E1 and E2 form the N terminus of the polyprotein and are the structural components of HCV virions.