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U1 small nuclear ribonucleoprotein A
go.drugbank.com/bio_entities/BE0002708TargetHumansIn a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs
Polypeptides: U1 small nuclear ribonucleoprotein ASynonyms: U1-A, U1 snRNP AMyocardin-related transcription factor A
go.drugbank.com/bio_entities/BE0004156TargetHumansTranscription coactivator that associates with the serum response factor (SRF) transcription factor to control expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration (PubMed:26224645). The SR...
Polypeptides: Myocardin-related transcription factor ASynonyms: MRTF-AEphrin type-A receptor 5
go.drugbank.com/bio_entities/BE0005587TargetHumansAmong GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. … Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis.
Polypeptides: Ephrin type-A receptor 5Acyl-coenzyme A thioesterase 1
go.drugbank.com/bio_entities/BE0016368EnzymeHumansCatalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels.
Polypeptides: Acyl-coenzyme A thioesterase 1Synonyms: Palmitoyl-coenzyme A thioesterase, Inducible cytosolic acyl-coenzyme A thioester hydrolaseLormetazepam
go.drugbank.com/drugs/DB13872ApprovedIt is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations. … Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia [L927].
Synonyms: N-Methyllorazepam, 7-Chloro-1,3-dihydro-5-(o-chlorophenyl)-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-oneCategories: Heterocyclic Compounds, 2-RingZinc oxide
go.drugbank.com/drugs/DB09321ApprovedInvestigationalZinc oxide is an inorganic compound used in a number of manufacturing processes. … It is also widely used to treat a variety of other skin conditions, in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments
Mixtures: Limited Line Edition 2018 MISSHA M Perfect Cover BB No 23, Limited Line Edition 2018 MISSHA M Perfect Cover BB No 21Categories: Compounds used in a research, industrial, or household settingDuloxetine
go.drugbank.com/drugs/DB00476ApprovedInvestigationalDuloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. … [L6454] It has since received approval for a variety of indications including the treatment of neuropathic pain, Generalized Anxiety disorder, osteoarthritis, and stress incontinence.
Synonyms: (3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine, (S)-duloxetineCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesOmega-3 fatty acids
go.drugbank.com/drugs/DB11133ApprovedInvestigationalNutraceuticalOmega-3 fatty acids are polyunsaturated fatty acids (PUFAs) with a double bond at the third carbon atom from the end of the carbon chain. … Omega-3 fatty acids play a critical role in metabolism and cellular function and they are available as daily supplements. On September 8, 2004, the U.S.
Synonyms: n-3 PUFAs, n-3 fatty acidsMixtures: Lipidem 200mg/ml Emulsion for Infusion, SetonET-ECOrlistat
go.drugbank.com/drugs/DB01083ApprovedInvestigationalIt was approved by the FDA for use in combination with a reduced-calorie diet in 1999. … [A229928] Orlistat is a lipase inhibitor used in the treatment of obesity that works by inhibiting fat-metabolizing enzymes.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: ORLISTAT EG, FINOBES ® 120 MG.Colchicine
go.drugbank.com/drugs/DB01394ApprovedInvestigationalColchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum autumnale_, or "autumn crocus."[A183611] Its use was first approved by the FDA in 1961. … [L47591] It has also been investigated in other inflammatory and fibrotic conditions.[A183602]
Categories: Preparations With No Effect on Uric Acid Metabolism, P-glycoprotein inducersProducts: Colctab 1 mg Tabletten, Colchanova 1 mg Tabletten