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Bromhexine
go.drugbank.com/drugs/DB09019ApprovedInvestigationalBromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducin...
Mixtures: BODREX FLU & BATUK BERDAHAK PEProducts: HUSTAB PLeucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
go.drugbank.com/bio_entities/BE0018277TargetHumansFunctional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:
Polypeptides: Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1Synonyms: Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6AMomelotinib
go.drugbank.com/drugs/DB11763ApprovedInvestigationalMF includes primary MF (PMF), post-polycythemia vera (PV) MF, and post-essential thrombocythemia (ET) MF. Clinical manifestations of MF include anemia and thrombocytosis.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesDoconexent
go.drugbank.com/drugs/DB03756ApprovedInvestigationalA mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. It can be biosythesized from alpha-linolenic aci...
Mixtures: Se-Tan DHA, Se-Tan DHACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsDopamine receptor D1
go.drugbank.com/bio_entities/BE0000020TargetHumansAlso acts as a receptor for D-lysergic (LSD) psychedelic drug (PubMed:39094559) … DRD1 can also couple with G(q) by forming a heteromer with the ghrelin receptor GHSR in hippocampal neurons independently of ghrelin (By similarity).
Polypeptides: Dopamine receptor D1Synonyms: Dopamine D1 receptor, D(1A) dopamine receptorGrowth hormone receptor
go.drugbank.com/bio_entities/BE0000075TargetHumansReceptor for pituitary gland growth hormone (GH1) involved in regulating postnatal body growth (PubMed:1549776, PubMed:2825030, PubMed:8943276).
Polypeptides: Growth hormone receptorSynonyms: GH receptor, Somatotropin receptorDopamine receptor D5
go.drugbank.com/bio_entities/BE0000145TargetHumansG protein-coupled receptor for dopamine, a catecholamine neurotransmitter hormone that functions as the brain's 'reward chemical', driving motivation, reinforcement learning and pleasure (PubMed:11500503 … Dopamine receptors can be classified in two categories: (1) DRD5 (together with DRD1) is a D1-type receptor and is coupled to G(s) G proteins, mediating activation of adenylate cyclase activity, while
Polypeptides: Dopamine receptor D5Synonyms: D(1B) dopamine receptor, Dopamine D5 receptorAdenosine receptor A2b
go.drugbank.com/bio_entities/BE0000241TargetHumansReceptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase
Polypeptides: Adenosine receptor A2bFunction: G protein-coupled adenosine receptor activityFolate receptor beta
go.drugbank.com/bio_entities/BE0000271TargetTransporterHumansExposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release
Polypeptides: Folate receptor betaSynonyms: Folate receptor 2, Folate receptor, fetal/placentalVasopressin V2 receptor
go.drugbank.com/bio_entities/BE0000293TargetHumansG protein-coupled receptor for arginine vasopressin, an antidiuretic that promotes renal water reabsorption (PubMed:1534149, PubMed:19440390, PubMed:33664408, PubMed:33742150).
Polypeptides: Vasopressin V2 receptorSynonyms: Antidiuretic hormone receptor, Renal-type arginine vasopressin receptor