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Free fatty acid receptor 4
go.drugbank.com/bio_entities/BE0003399TargetHumansG protein-coupled receptor for long-chain fatty acids (LCFAs) with a major role in adipogenesis, energy metabolism and inflammation. Signals via G protein and beta-arrestin pathways (PubMed:22282525, PubMed:22343897, PubMed:24742677, Pub...
Polypeptides: Free fatty acid receptor 4Collagen alpha-4(IV) chain
go.drugbank.com/bio_entities/BE0003498TargetHumansType IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen
Polypeptides: Collagen alpha-4(IV) chainDNA polymerase epsilon subunit 4
go.drugbank.com/bio_entities/BE0003616TargetHumansAccessory component of the DNA polymerase epsilon complex (PubMed:10801849). Participates in DNA repair and in chromosomal DNA replication (By similarity)
Polypeptides: DNA polymerase epsilon subunit 4Synonyms: DNA polymerase II subunit 4Electrogenic sodium bicarbonate cotransporter 4
go.drugbank.com/bio_entities/BE0004677TransporterHumansMediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3
Polypeptides: Electrogenic sodium bicarbonate cotransporter 4Synonyms: Solute carrier family 4 member 5DNA topoisomerase 4 subunit B
go.drugbank.com/bio_entities/BE0008386TargetBacillus subtilis (strain 168)Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.
Polypeptides: DNA topoisomerase 4 subunit BSecreted frizzled-related protein 4
go.drugbank.com/bio_entities/BE0009094TargetHumansSoluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types (By similarity). SFRP4 plays a ...
Polypeptides: Secreted frizzled-related protein 4Synonyms: sFRP-4Sphingolipid delta(4)-desaturase DES1
go.drugbank.com/bio_entities/BE0011584TargetHumansHas sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) (PubMed:11937514, PubMed:30620337, PubMed:30620338).
Polypeptides: Sphingolipid delta(4)-desaturase DES1Transcriptional enhancer factor TEF-4
go.drugbank.com/bio_entities/BE0014575TargetHumansTranscription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a ki...
Polypeptides: Transcriptional enhancer factor TEF-4Cinpanemab
go.drugbank.com/drugs/DB16127InvestigationalCinpanemab is under investigation in clinical trial NCT03318523 (Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of BIIB054 in Participants With Parkinson's Disease).
Synonyms: Immunoglobulin g1-lambda, anti-(homo sapiens snca (synuclein alpha, alpha-synuclein, park1, park4, parkinson disease (autosomal dominant, lewy body) 4, non a4 component of amyloid precursor, nacp)), monoclonal, Immunoglobulin g1-lambda, anti-(homo sapiens alpha-synuclein)humanized monoclonal antibody.gamma.1 heavy chain (1-442) (homo sapiens vh (ighv3-25*03 (86%) (ighd)-ighj2*01) (8.10.4) (1-113)-homo sapiensLevetiracetam
go.drugbank.com/drugs/DB01202ApprovedInvestigationalmake it a desirable choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and a propensity for involvement in drug interactions. … Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders.
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingProducts: 6-UR, KEPPRA 100 MG/ML LSG Z EIN