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DTDP-4-dehydrorhamnose 3,5-epimerase
go.drugbank.com/bio_entities/BE0002995TargetStreptococcus suisPolypeptides: dTDP-4-dehydrorhamnose 3,5-epimeraseFunction: dTDP-4-dehydrorhamnose 3,5-epimerase activityType-4 uracil-DNA glycosylase
go.drugbank.com/bio_entities/BE0003080TargetThermus thermophilusRemoves uracil bases that are present in DNA as a result of either deamination of cytosine or misincorporation of dUMP instead of dTMP. Can remove uracil from double-stranded DNA containing either a U/G, U/A, U/C or U/T base pair as well...
Polypeptides: Type-4 uracil-DNA glycosylaseFunction: 4 iron, 4 sulfur cluster bindingHepatocyte nuclear factor 4-gamma
go.drugbank.com/bio_entities/BE0003179TargetHumansTranscription factor. Has a lower transcription activation potential than HNF4-alpha
Polypeptides: Hepatocyte nuclear factor 4-gammaSynonyms: HNF-4-gammaDNA topoisomerase 4 subunit B
go.drugbank.com/bio_entities/BE0003294TargetEscherichia coli (strain K12)Topoisomerase IV is essential for chromosome segregation; it is the principal protein responsible for decatenating newly replicated chromosomes (PubMed:9334322). It relaxes supercoiled DNA (PubMed:15105144, PubMed:21300644, PubMed:232946...
Polypeptides: DNA topoisomerase 4 subunit BFree fatty acid receptor 4
go.drugbank.com/bio_entities/BE0003399TargetHumansG protein-coupled receptor for long-chain fatty acids (LCFAs) with a major role in adipogenesis, energy metabolism and inflammation. Signals via G protein and beta-arrestin pathways (PubMed:22282525, PubMed:22343897, PubMed:24742677, Pub...
Polypeptides: Free fatty acid receptor 4Collagen alpha-4(IV) chain
go.drugbank.com/bio_entities/BE0003498TargetHumansType IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen
Polypeptides: Collagen alpha-4(IV) chainDNA polymerase epsilon subunit 4
go.drugbank.com/bio_entities/BE0003616TargetHumansAccessory component of the DNA polymerase epsilon complex (PubMed:10801849). Participates in DNA repair and in chromosomal DNA replication (By similarity)
Polypeptides: DNA polymerase epsilon subunit 4Synonyms: DNA polymerase II subunit 4Electrogenic sodium bicarbonate cotransporter 4
go.drugbank.com/bio_entities/BE0004677TransporterHumansMediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3
Polypeptides: Electrogenic sodium bicarbonate cotransporter 4Synonyms: Solute carrier family 4 member 5DNA topoisomerase 4 subunit B
go.drugbank.com/bio_entities/BE0008386TargetBacillus subtilis (strain 168)Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.
Polypeptides: DNA topoisomerase 4 subunit BSecreted frizzled-related protein 4
go.drugbank.com/bio_entities/BE0009094TargetHumansSoluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types (By similarity). SFRP4 plays a ...
Polypeptides: Secreted frizzled-related protein 4Synonyms: sFRP-4