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Displaying results 4481 - 4490 of 10000 in total
  1. Target

    Interleukin-4 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0002420
    TargetHumans

    Receptor for both interleukin 4 and interleukin 13 (PubMed:17030238). Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation.

    Polypeptides: Interleukin-4 receptor subunit alphaSynonyms: IL-4 receptor subunit alpha
  2. Target

    Ephrin type-B receptor 4

    go.drugbank.com/bio_entities/BE0002453
    TargetHumans

    Together with its cognate ligand/functional ligand EFNB2, it is involved in the regulation of cell adhesion and migration, and plays a central role in heart morphogenesis, angiogenesis and blood vessel

    Polypeptides: Ephrin type-B receptor 4
  3. Target

    DTDP-4-dehydrorhamnose 3,5-epimerase

    go.drugbank.com/bio_entities/BE0002995
    TargetStreptococcus suis

    Polypeptides: dTDP-4-dehydrorhamnose 3,5-epimeraseFunction: dTDP-4-dehydrorhamnose 3,5-epimerase activity
  4. Target

    Type-4 uracil-DNA glycosylase

    go.drugbank.com/bio_entities/BE0003080
    TargetThermus thermophilus

    Can remove uracil from double-stranded DNA containing either a U/G, U/A, U/C or U/T base pair as well as from single-stranded DNA (PubMed:12000829, PubMed:14556741). … Removes uracil bases that are present in DNA as a result of either deamination of cytosine or misincorporation of dUMP instead of dTMP.

    Polypeptides: Type-4 uracil-DNA glycosylaseFunction: 4 iron, 4 sulfur cluster binding
  5. Target

    Hepatocyte nuclear factor 4-gamma

    go.drugbank.com/bio_entities/BE0003179
    TargetHumans

    Has a lower transcription activation potential than HNF4-alpha

    Polypeptides: Hepatocyte nuclear factor 4-gammaSynonyms: HNF-4-gamma, Nuclear receptor subfamily 2 group A member 2
  6. Target

    DNA topoisomerase 4 subunit B

    go.drugbank.com/bio_entities/BE0003294
    TargetEscherichia coli (strain K12)

    MukB stimulates the relaxation activity of topoisomerase IV and also has a modest effect on decatenation (PubMed:20921377).

    Polypeptides: DNA topoisomerase 4 subunit B
  7. Target

    Free fatty acid receptor 4

    go.drugbank.com/bio_entities/BE0003399
    TargetHumans

    G protein-coupled receptor for long-chain fatty acids (LCFAs) with a major role in adipogenesis, energy metabolism and inflammation. … LCFAs sensing initiates activation of phosphoinositidase C-linked G proteins GNAQ and GNA11 (G(q)/G(11)), inducing a variety of cellular responses via second messenger pathways such as intracellular calcium

    Polypeptides: Free fatty acid receptor 4
  8. Target

    Collagen alpha-4(IV) chain

    go.drugbank.com/bio_entities/BE0003498
    TargetHumans

    Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen

    Polypeptides: Collagen alpha-4(IV) chain
  9. Target

    DNA polymerase epsilon subunit 4

    go.drugbank.com/bio_entities/BE0003616
    TargetHumans

    Accessory component of the DNA polymerase epsilon complex (PubMed:10801849). Participates in DNA repair and in chromosomal DNA replication (By similarity)

    Polypeptides: DNA polymerase epsilon subunit 4Synonyms: DNA polymerase II subunit 4
  10. Target

    Electrogenic sodium bicarbonate cotransporter 4

    go.drugbank.com/bio_entities/BE0004677
    TransporterHumans

    Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3

    Polypeptides: Electrogenic sodium bicarbonate cotransporter 4Synonyms: Solute carrier family 4 member 5