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Displaying results 4591 - 4600 of 10000 in total
  1. Drug

    Von Willebrand factor human

    go.drugbank.com/drugs/DB13133
    ApprovedInvestigational

    It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). … The human vWF is used to manage and control bleeding episodes in patients with von Willebrand disease and hemophilia A. It was first approved by the FDA in 2015.

    Mixtures: BIOSTATE FOR INJECTION 50 iu/ml, IMMUNATE 500 IU/375 IU IV INFUZYONLUK TOZ ICEREN FLAKON, 1 ADETProducts: IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION, IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION
  2. Drug

    Phenol

    go.drugbank.com/drugs/DB03255
    ApprovedInvestigational

    It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. … During the second world war, phenol injections were used as a means of execution by the Nazis. Phenol is a toxic compound whose vapours are corrosive to the skin, eyes, and respiratory tract.

    Mixtures: DİŞİNOL 2 G + 0,5 G + 3,5 G/10 ML ÇÖZELTİ, COOLING 5 PLUSCategories: Compounds used in a research, industrial, or household setting
  3. Drug

    Doxylamine

    go.drugbank.com/drugs/DB00366
    ApprovedInvestigationalVet approved

    It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.

    Synonyms: N,N-Dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine, Phenyl-2-pyridylmethyl-beta-N,N-dimethylaminoethyl etherMixtures: PRİLAM DR 10 MG/10 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 ADET, PRİFEMYN DR 10 MG/10 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 ADET
  4. Drug

    Inotuzumab ozogamicin

    go.drugbank.com/drugs/DB05889
    ApprovedInvestigational

    Inotuzumab ozogamicin is an antibody-drug conjugate consisting of a humanized IgG4 kappa CD22-targeting monoclonal antibody covalently attached to calicheamicin derivative, N-acetyl-gamma-calicheamicin … [L938] A month later, inotuzumab ozogamicin was also approved by the FDA.[L50542]

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein substratesProducts: BESPONSA 1 MG IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET, BESPONSA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 1MG/VIAL
  5. Drug

    Pentostatin

    go.drugbank.com/drugs/DB00552
    ApprovedInvestigational

    It is also synergistic with some other antineoplastic agents and has immunosuppressive activity. … A potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia.

    Categories: Heterocyclic Compounds, 1-Ring, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: CIPROFLOXACINO TABLETAS RECUBIERTAS 500 MG.
  6. Pathway

    Acylcarnitine (10E)-8-Hydroxydodec-10-enoylcarnitine

    smpdb.ca/view/SMP0124017
    Metabolic

    (10E)-8-Hydroxydodec-10-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (10E)-8-hydroxydodec-10-enoyl-CoA reacts with L-carnitine to form (10E)-8-hydroxydodec-10-enoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  7. Drug

    Dolichovespula maculata venom protein

    go.drugbank.com/drugs/DB10958
    Approved

    Dolichovespula maculata venom protein is an extract of Dolichovespula maculata venom. Dolichovespula maculata venom protein is used in allergenic testing.

    Mixtures: Mixed Vespid Venom Protein Multidose 13.0 Ml (3900 Mcg), Hymenoptera Venom Product-mixed Vespid Venom Protein (1650 Mcg)Products: Venomil Inj 10mcg/ml White Faced Hornet, Venomil Inj 100mcg/ml White Faced Hornet
  8. Drug

    Selexipag

    go.drugbank.com/drugs/DB11362
    ApprovedInvestigational

    PAH is a relatively rare disease with usually a poor prognosis requiring more treatment options to prolong long-term outcomes.

    Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesProducts: UPTRAVI 200 MCG FILM KAPLI TABLET, 140 ADET, SELPENZA 200 MCG FİLM KAPLI TABLET, 140 ADET
  9. Drug

    Perflutren

    go.drugbank.com/drugs/DB00556
    ApprovedInvestigational

    Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane

    Mixtures: Optison Perflutren Protein-Type A MicrospheresCategories: Compounds used in a research, industrial, or household setting
  10. Drug

    Human cytomegalovirus immune globulin

    go.drugbank.com/drugs/DB13886
    ApprovedInvestigational

    It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label]. … The seroprevalence of antibodies in adults ranges from 40-100 % with an inverse correlation to socioeconomic status.

    Categories: Immunoglobulin G, Human Immunoglobulin GProducts: MEGALOTECT CP SOLUTION FOR INFUSION 100 U/ML