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SEC14-like protein 2
go.drugbank.com/bio_entities/BE0000256TargetTransporterCarrierHumansCarrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrieno...
Polypeptides: SEC14-like protein 2Mitochondrial ornithine transporter 2
go.drugbank.com/bio_entities/BE0000258TargetHumansMitochondrial transporter of the positively charged amino acids ornithine, lysine and arginine, and the neutral amino acid citrulline (PubMed:12807890). In addition, transports the basic amino acids histidine, homoarginine, and asymmetri...
Polypeptides: Mitochondrial ornithine transporter 2Synonyms: Solute carrier family 25 member 2Interferon gamma receptor 2
go.drugbank.com/bio_entities/BE0000467TargetHumansAssociates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:7673114, PubMed:8124716). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:15356148, PubMed:7673114,...
Polypeptides: Interferon gamma receptor 2Synonyms: IFN-gamma receptor 2ADP/ATP translocase 2
go.drugbank.com/bio_entities/BE0000709TargetHumansADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity). Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-stat...
Polypeptides: ADP/ATP translocase 2Synonyms: ANT 2, ADP,ATP carrier protein 2Glutamate dehydrogenase 2, mitochondrial
go.drugbank.com/bio_entities/BE0000755TargetHumansCatalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia (PubMed:11032875). Plays a key role in glutamate metabolism and energy production via the TCA cycle in neural and testicular tissues (PubMed:11032875). I...
Polypeptides: Glutamate dehydrogenase 2, mitochondrialSynonyms: GDH 2Chloride channel protein 2
go.drugbank.com/bio_entities/BE0000765TargetHumansVoltage-gated and osmosensitive chloride channel. Forms a homodimeric channel where each subunit has its own ion conduction pathway. Conducts double-barreled currents controlled by two types of gates, two fast glutamate gates that contro...
Polypeptides: Chloride channel protein 2Synonyms: ClC-2Bifunctional epoxide hydrolase 2
go.drugbank.com/bio_entities/BE0000950TargetEnzymeHumansBifunctional enzyme (PubMed:12574510). The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides (PubMed:12574510, PubMed:12869654, PubMed:22798687). Plays a role in xenobiotic m...
Polypeptides: Bifunctional epoxide hydrolase 2Metabotropic glutamate receptor 2
go.drugbank.com/bio_entities/BE0000974TargetHumansDimeric G protein-coupled receptor which is activated by the excitatory neurotransmitter L-glutamate (PubMed:37286794). Plays critical roles in modulating synaptic transmission and neuronal excitability. Upon activation by glutamate, inh...
Polypeptides: Metabotropic glutamate receptor 2Fibroblast growth factor 2
go.drugbank.com/bio_entities/BE0001015TargetHumansMediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (PubMed:29501879)
Polypeptides: Fibroblast growth factor 2Synonyms: FGF-2, HBGF-2Cyclin-dependent kinase 2
go.drugbank.com/bio_entities/BE0001072TargetHumansSerine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis (PubMed:10499802, PubMed:10884347, PubMed:10995386, PubMed:10995387, PubMed:11051553, PubMed:11113184, PubMed:1...
Polypeptides: Cyclin-dependent kinase 2Synonyms: Cell division protein kinase 2