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Proteinase-activated receptor 2
go.drugbank.com/bio_entities/BE0010726TargetHumansAssociates with a subset of G proteins alpha subunits such as GNAQ, GNA11, GNA14, GNA12 and GNA13, but probably not with G(o)-alpha, G(i) subunit alpha-1 and G(i) subunit alpha-2.
Polypeptides: Proteinase-activated receptor 2Synonyms: PAR-2Apoptosis regulator Bcl-2
go.drugbank.com/bio_entities/BE0010919TargetRatSuppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system...
Polypeptides: Apoptosis regulator Bcl-2Synonyms: Bcl-2CCN family member 2
go.drugbank.com/bio_entities/BE0013178TargetHumansMajor connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenes...
Polypeptides: CCN family member 2Synonyms: Cellular communication network factor 2Lysosome membrane protein 2
go.drugbank.com/bio_entities/BE0014604TransporterHumansActs as a lysosomal receptor for glucosylceramidase (GBA1) targeting
Polypeptides: Lysosome membrane protein 2Synonyms: CD36 antigen-like 2, Scavenger receptor class B member 2Pantothenate kinase 2, mitochondrial
go.drugbank.com/bio_entities/BE0019249EnzymeHumansMitochondrial isoform that catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis (PubMed:15659606, PubMed:16272150, PubMed:17242360, PubMed:1...
Polypeptides: Pantothenate kinase 2, mitochondrialSynonyms: Pantothenic acid kinase 2Inositol-pentakisphosphate 2-kinase
go.drugbank.com/bio_entities/BE0019971EnzymeHumansPhosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
Polypeptides: Inositol-pentakisphosphate 2-kinaseSynonyms: InsP5 2-kinase, Ins(1,3,4,5,6)P5 2-kinaserRNA methyltransferase 2, mitochondrial
go.drugbank.com/bio_entities/BE0020789TargetHumansS-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU … This activity may require prior 2'-O-methylguanosine modification at position 1370 (Gm1370) by MRM3 (PubMed:35177605).
Polypeptides: rRNA methyltransferase 2, mitochondrialSynonyms: Protein ftsJ homolog 2, 16S rRNA [Um1369] 2'-O-methyltransferaseInsulin receptor substrate 2
go.drugbank.com/bio_entities/BE0021286TargetHumansSignaling adapter protein that participates in the signal transduction from two prominent receptor tyrosine kinases, insulin receptor/INSR and insulin-like growth factor I receptor/IGF1R (PubMed:25879670). Plays therefore an important ro...
Polypeptides: Insulin receptor substrate 2Synonyms: IRS-2Zinc sulfate
go.drugbank.com/drugs/DB09322ApprovedInvestigationalIt is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Mixtures: /g + 5 mg/g Gel, M T E 4 Concentrate InjProducts: FORTZINK JARABE 20 MG/5 ML, ZİNCO 25 MG/5 ML ŞURUP, 100 MLRotavirus vaccine
go.drugbank.com/drugs/DB10276ApprovedInvestigationalRotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains.[L1116] Rotarix is a live attenuated vaccine containing the 89-12 human strain.
Salts: Human Rotavirus A type G1P(8) strain RIX4414 live antigen, Human Rotavirus A type G1P7(5) strain WI79 live antigenMixtures: ROTATEQ® VACUNA ORAL PENTAVALENTE CONTRAROTAVIRUS, ROTATEQ® VACUNA ORAL PENTAVALENTE CONTRAROTAVIRUS