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Aldo-keto reductase family 1 member B1
go.drugbank.com/bio_entities/BE0000747TargetEnzymeHumansCatalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols.
Cocaine esterase
go.drugbank.com/bio_entities/BE0001413TargetEnzymeRhodococcus sp. (strain MB1 Bresler)Also efficiently hydrolyzes cocaethylene, a more potent cocaine metabolite that has been observed in patients who concurrently abuse cocaine and alcohol.
NADP-dependent isopropanol dehydrogenase
go.drugbank.com/bio_entities/BE0001892TargetThermoanaerobacter brockiiAlcohol dehydrogenase with a preference for medium chain secondary alcohols, such as 2-butanol and isopropanol. Has very low activity with primary alcohols, such as ethanol. … Under physiological conditions, the enzyme reduces aldehydes and 2-ketones to produce secondary alcohols. Is also active with acetaldehyde and propionaldehyde.
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
go.drugbank.com/bio_entities/BE0002199TargetHumansCatalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthas...
Function: alcohol bindingPeroxiredoxin
go.drugbank.com/bio_entities/BE0003140TargetEnzymePlasmodium falciparum (isolate 3D7)Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.
Esterase EstB
go.drugbank.com/bio_entities/BE0003305TargetPseudomonas marginataActs on short-chain (C4-C6) fatty acid esters and triglycerides, including tertiary alcohol esters. Activity on p-nitrophenyl esters is generally higher than on o-nitrophenyl esters.
Cytochrome P450 2C19
go.drugbank.com/bio_entities/BE0003536EnzymeTargetHumansOxygenates (R)- and (S)-limonene to produce carveol and perillyl alcohol (PubMed:11950794).
Serine hydrolase BPHL
go.drugbank.com/bio_entities/BE0004370TargetHumansSpecific alpha-amino acid ester serine hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol
Tartrate-resistant acid phosphatase type 5
go.drugbank.com/bio_entities/BE0004487TargetHumansFunctions as a binuclear Fe(III)-Fe(II) acid phosphatase that hydrolyzes phosphate esters to alcohols and phosphate under acidic conditions (PubMed:1477968, PubMed:2775236).
Peroxiredoxin-6
go.drugbank.com/bio_entities/BE0004641TargetHumansThiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively (PubMed:10893423, PubMed:9497358).