Search

Displaying results 41 - 50 of 485 in total
  1. Target

    Alpha-1-acid glycoprotein 1

    go.drugbank.com/bio_entities/BE0000925
    CarrierTargetHumans

    Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction

    Polypeptides: Alpha-1-acid glycoprotein 1
  2. Target

    Excitatory amino acid transporter 1

    go.drugbank.com/bio_entities/BE0001115
    TargetTransporterHumans

    Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:20477940). … Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:20477940, PubMed:26690923, PubMed:28032905, PubMed:28424515,

    Polypeptides: Excitatory amino acid transporter 1
  3. Target

    Fatty acid-binding protein, heart

    go.drugbank.com/bio_entities/BE0001201
    CarrierHumans

    FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters

    Polypeptides: Fatty acid-binding protein, heartSynonyms: Fatty acid-binding protein 3, Muscle fatty acid-binding protein
  4. Target

    Fatty-acid amide hydrolase 1

    go.drugbank.com/bio_entities/BE0002194
    TargetEnzymeHumans

    FAAH cooperates with PM20D1 in the hydrolysis of amino acid-conjugated fatty acids such as N-fatty acyl glycine and N-fatty acyl-L-serine, thereby acting as a physiological regulator of specific subsets … Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates (PubMed:17015445, PubMed:9122178).

    Polypeptides: Fatty-acid amide hydrolase 1Synonyms: Fatty acid ester hydrolase
  5. Target

    Excitatory amino acid transporter 5

    go.drugbank.com/bio_entities/BE0002267
    TargetHumans

    Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. … Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:9108121).

    Polypeptides: Excitatory amino acid transporter 5
  6. Target

    Vesicular inhibitory amino acid transporter

    go.drugbank.com/bio_entities/BE0002308
    TransporterHumans

    The transport is equally dependent on the chemical and electrical components of the proton gradient (By similarity). May also transport beta-alanine (By similarity). … Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals.

    Polypeptides: Vesicular inhibitory amino acid transporterSynonyms: GABA and glycine transporter
  7. Target

    Cyclopropane mycolic acid synthase 3

    go.drugbank.com/bio_entities/BE0002521
    TargetMycobacterium tuberculosis

    It can use cis, cis 11,14-eicosadienoic acid and linoelaidic acid as substrate. … Catalyzes the conversion of a double bond to a cyclopropane ring at the proximal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.

    Polypeptides: Cyclopropane mycolic acid synthase 3Synonyms: Cyclopropane fatty acid synthase, Mycolic acid methyltransferase
  8. Target

    Fatty acid metabolism regulator protein

    go.drugbank.com/bio_entities/BE0003045
    TargetBacillus subtilis (strain 168)

    Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. … Transcriptional regulator in fatty acid degradation.

    Polypeptides: Fatty acid metabolism regulator protein
  9. Target

    Fatty acid-binding protein TM_1468

    go.drugbank.com/bio_entities/BE0003182
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Binds long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.

    Polypeptides: Fatty acid-binding protein TM_1468
  10. Target

    Hepatic sodium/bile acid cotransporter

    go.drugbank.com/bio_entities/BE0003644
    TransporterTargetHumans

    Works collaboratively with the ileal transporter (NTCP2), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic … It exhibits broad substrate specificity and transports various bile acids, such as taurocholate, cholate, as well as non-bile acid organic compounds, such as estrone sulfate (PubMed:14660639, PubMed:34060352

    Polypeptides: Hepatic sodium/bile acid cotransporterSynonyms: Na(+)/bile acid cotransporter