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Ethylmorphine Action Pathway
smpdb.ca/view/SMP0000681Drug actionMorphine can also bind and inhibit gamma-Aminobutyric acid (GABA) inhibitory interneurons. … Ethylmorphine (also known as codethyline and dionine) is an opioid analgesic. Ethylmorphine can be metabolized to form morphine by cytochrome P450 2D6 (CYP2D6).
Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporterPentazocine Action Pathway
smpdb.ca/view/SMP0000686Drug actionBinding of pentazocine on mu-type opioid receptor and kappa-type opioid receptor can lead to decreased level of neuronal excitability and hyperpolarization. … Pentazocine can bind to mu-type opioid receptor and kappa-type opioid receptor on neuron of central nerves system (CNS).
Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporterHeroin Action Pathway
smpdb.ca/view/SMP0000407Drug actionThey are beta-endorphin, dynorphin, leu-enkephalin, and met-enkephalin. … Endorphins are regularly released in the brain and nerves, attenuating pain.
Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporterOxycodone Action Pathway
smpdb.ca/view/SMP0000409Drug actionThe binding of oxycodone will eventually lead to reduced pain because of decreased nerve conduction and release of neurotransmitter. … Hyperpolarization of neuron is caused by inactivation of calcium channels and activation of potassium channels via facilitated by G-protein.
Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporterFentanyl Action Pathway
smpdb.ca/view/SMP0000415Drug actionThe binding of carfentanil will eventually lead to reduced pain because of decreased nerve conduction and release of neurotransmitter. … Hyperpolarization of neuron is caused by inactivation of calcium channels and activation of potassium channels via facilitated by G-protein.
Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporterDezocine Action Pathway
smpdb.ca/view/SMP0000676Drug actionThe binding of dezocine will eventually lead to reduced pain because of decreased nerve conduction and release of neurotransmitter. … Hyperpolarization of neuron is caused by inactivation of calcium channels and activation of potassium channels via facilitated by G-protein.
Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporterLevallorphan Action Pathway
smpdb.ca/view/SMP0000683Drug actionLevallorphan (also known as Lorfan and Naloxifan) is a type of medication that can be used for treating drug overdoses and respirotry depression. … Levallorphan can bind to mu-type opioid receptor and kappa-type opioid receptor on neuron of central nerves system (CNS).
Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporterBuprenorphine Action Pathway
smpdb.ca/view/SMP0000684Drug actionand symptoms of withdrawal. … Buprenorphine, trade name subutex, suboxone, zubsolv and bunavail, is a partial agonist of mu-opioid receptors and a kappa-opioid receptor antagonist and is prescribed for opioid addiction to prevent cravings
Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporterNaltrexone Action Pathway
smpdb.ca/view/SMP0000687Drug actionNaltrexone (also known as ReVia and Vivitrol) is a competitive antagonist of mu-type opioid receptor in the central nervous system (CNS).
Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporterDihydromorphine Action Pathway
smpdb.ca/view/SMP0000689Drug actionHyperpolarization of neuron is caused by inactivation of calcium channels and activation of potassium channels via facilitated by G-protein. … The binding of dihydromorphine acetate will eventually lead to reduced pain because of decreased nerve conduction and release of neurotransmitter.
Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporter