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Trastuzumab
go.drugbank.com/drugs/DB00072ApprovedInvestigationaldomain of the human epidermal growth factor receptor protein (HER2). … Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody [A40276] that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular
Categories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitorsHepatocellular Carcinoma
go.drugbank.com/conditions/DBCOND0030090Drugs: Cabozantinib · Capecitabine · Hyaluronidase (human recombinant) · Ipilimumab · Nivolumab · Pembrolizumab +2 moreStage I Breast Cancer
go.drugbank.com/conditions/DBCOND0029483Drugs: Anastrozole · Exemestane · Hyaluronidase (human recombinant) · Letrozole · Olaparib · Pertuzumab +1 morePrimary Amyloidosis
go.drugbank.com/conditions/DBCOND0040057Drugs: Bortezomib · Cyclophosphamide · Daratumumab · Dexamethasone · Hyaluronidase (human recombinant) · Lenalidomide +1 moreGeneralized Myasthenia Gravis
go.drugbank.com/conditions/DBCOND0037937Drugs: Eculizumab · Efgartigimod alfa · Hyaluronidase (human recombinant) · Inebilizumab · Nipocalimab · Ravulizumab +2 moreUnresectable Melanoma
go.drugbank.com/conditions/DBCOND0047213Drugs: Atezolizumab · Binimetinib · Cobimetinib · Dabrafenib · Encorafenib · Hyaluronidase (human recombinant) +7 moreAdvanced Renal Cell Carcinoma
go.drugbank.com/conditions/DBCOND0032596Drugs: Avelumab · Axitinib · Belzutifan · Cabozantinib · Hyaluronidase (human recombinant) · Lenvatinib +6 moreLocally Advanced Breast Cancer (LABC)
go.drugbank.com/conditions/DBCOND0034432Drugs: Anastrozole · Docetaxel · Elacestrant · Hyaluronidase (human recombinant) · Ixabepilone · Olaparib +4 moreRituximab
go.drugbank.com/drugs/DB00073ApprovedInvestigationalThe antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences. … Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes.
Teclistamab
go.drugbank.com/drugs/DB16655ApprovedInvestigationalTeclistamab is an IgG4-PAA bispecific antibody that targets the CD3 receptor expressed on the surface of T cells and B cell maturation antigen (BCMA) expressed on malignant multiple myeloma cells. Teclistamab consists of an anti-BCMA arm...