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Solute carrier family 12 member 2
go.drugbank.com/bio_entities/BE0000281TargetTransporterHumansCation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane (PubMed:16669787, PubMed:32081947, PubMed:32294086, PubMed:33597714, PubMed:35585053, PubMed:36239040...
Polypeptides: Solute carrier family 12 member 2Synonyms: Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2S-adenosylmethionine synthase isoform type-2
go.drugbank.com/bio_entities/BE0000304TargetEnzymeHumansCatalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis ...
Polypeptides: S-adenosylmethionine synthase isoform type-2Synonyms: MAT 2, AdoMet synthase 2Vascular endothelial growth factor receptor 2
go.drugbank.com/bio_entities/BE0000369TargetHumansIsoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. … Isoform 2 plays an important role as negative regulator of VEGFA- and VEGFC-mediated lymphangiogenesis by limiting the amount of free VEGFA and/or VEGFC and preventing their binding to FLT4.
Polypeptides: Vascular endothelial growth factor receptor 2Synonyms: VEGFR-2Taste receptor type 1 member 2
go.drugbank.com/bio_entities/BE0000395TargetHumansKey component of the sweet taste receptor (PubMed:11917125, PubMed:40339580, PubMed:40754567, PubMed:40555359). TAS1R2 and TAS1R3 form the sweet taste receptor and recognize diverse natural and synthetic sweeteners (PubMed:11917125, PubM...
Polypeptides: Taste receptor type 1 member 2Neuronal acetylcholine receptor subunit beta-2
go.drugbank.com/bio_entities/BE0000850TargetHumansFound in two major stoichiometric forms,(CHRNA4)3:(CHRNB2)2 and (CHRNA4)2:(CHRNB2)3, the two stoichiometric forms differ in their unitary conductance, calcium permeability, ACh sensitivity and potentiation
Polypeptides: Neuronal acetylcholine receptor subunit beta-2Prolyl 4-hydroxylase subunit alpha-2
go.drugbank.com/bio_entities/BE0002253TargetHumansCatalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins
Polypeptides: Prolyl 4-hydroxylase subunit alpha-2Synonyms: 4-PH alpha-2, Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2Glycine N-acyltransferase-like protein 2
go.drugbank.com/bio_entities/BE0002306TargetHumansMitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine (PubMed:20305126, PubMed:22475485). Conjugates numerous substrates, such as arachidonoyl-CoA and saturated medium and long-chain acyl-CoAs ranging ...
Polypeptides: Glycine N-acyltransferase-like protein 2Synonyms: Acyl-CoA:glycine N-acyltransferase-like protein 2Peroxisomal trans-2-enoyl-CoA reductase
go.drugbank.com/bio_entities/BE0002791TargetHumansCatalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA. Has no 2,4-dienoyl-CoA reductase activity
Polypeptides: Peroxisomal trans-2-enoyl-CoA reductaseC-C chemokine receptor type 2
go.drugbank.com/bio_entities/BE0003387TargetHumansKey functional receptor for CCL2 but can also bind CCL7, and CCL12 (PubMed:23408426, PubMed:38157855, PubMed:8048929, PubMed:8146186). Also transduces signaling mediated by CCL13 (PubMed:38157855). Its binding with CCL2 on monocytes and ...
Polypeptides: C-C chemokine receptor type 2Synonyms: CCR-2, CC-CKR-2Transforming growth factor beta-2 proprotein
go.drugbank.com/bio_entities/BE0003481TargetHumansPrecursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively
Polypeptides: Transforming growth factor beta-2 proprotein