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Piperazine
go.drugbank.com/drugs/DB00592ApprovedVet approvedWithdrawnOutside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. … Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: MEI-MEI WORM SYRUP 750 mg/5 ml, ASEPAR 100 MG 100 ML SURUPOlopatadine
go.drugbank.com/drugs/DB00768ApprovedIt is a structural analog of [doxepin], which has a minimal anti-allergic activity. … Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions.
Mixtures: OFNOL FRESH % 0.1 + %0.15 STERİL OFTALMİK ÇÖZELTİ, 1 ADETCategories: Cytochrome P-450 Substrates, P-glycoprotein substratesAcetyl-coenzyme A synthetase 2-like, mitochondrial
go.drugbank.com/bio_entities/BE0000746TargetHumansCatalyzes the synthesis of acetyl-CoA from short-chain fatty acids (PubMed:16788062). Acetate is the preferred substrate (PubMed:16788062). Can also utilize propionate with a much lower affinity (By similarity). Provides acetyl-CoA that ...
Polypeptides: Acetyl-coenzyme A synthetase 2-like, mitochondrialSynonyms: Acetate--CoA ligase 2, Acetyl-CoA synthetase 23-oxoacyl-[acyl-carrier-protein] synthase 2
go.drugbank.com/bio_entities/BE0000800TargetEscherichia coli (strain K12)Involved in the type II fatty acid elongation cycle (PubMed:6988423, PubMed:9013860). Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor (PubMed:22017312, PubMed:90138...
Polypeptides: 3-oxoacyl-[acyl-carrier-protein] synthase 2Low-density lipoprotein receptor-related protein 2
go.drugbank.com/bio_entities/BE0000942TargetTransporterHumansMediates endocytosis of angiotensin-2 (By similarity). Also mediates endocytosis of angiotensis 1-7 (By similarity).
Polypeptides: Low-density lipoprotein receptor-related protein 2Synonyms: LRP-22-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
go.drugbank.com/bio_entities/BE0001488TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.
Polypeptides: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinaseFunction: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity2-amino-3-ketobutyrate coenzyme A ligase
go.drugbank.com/bio_entities/BE0002049TargetEscherichia coli (strain K12)Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
Polypeptides: 2-amino-3-ketobutyrate coenzyme A ligaseSodium channel protein type 2 subunit alpha
go.drugbank.com/bio_entities/BE0002081TargetHumansMediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which ...
Polypeptides: Sodium channel protein type 2 subunit alphaSodium- and chloride-dependent glycine transporter 2
go.drugbank.com/bio_entities/BE0002310TransporterTargetHumansSodium- and chloride-dependent glycine transporter (PubMed:10381548, PubMed:10606742, PubMed:16751771, PubMed:31370103, PubMed:9845349). Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic ter...
Polypeptides: Sodium- and chloride-dependent glycine transporter 2Synonyms: GlyT-2Mitogen-activated protein kinase kinase kinase 2
go.drugbank.com/bio_entities/BE0004745TargetHumansComponent of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and-run dynamics
Polypeptides: Mitogen-activated protein kinase kinase kinase 2Synonyms: MEKK 2, MEK kinase 2