Search
Citric acid
go.drugbank.com/drugs/DB04272ApprovedInvestigationalNutraceuticalVet approvedCitric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020. … A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability.
Synonyms: 3-carboxy-3-hydroxypentane-1,5-dioic acid, 2-Hydroxytricarballylic acidMixtures: PICOPREP 10 MG / 3,5 G /12 G ORAL ÇÖZELTI IÇIN TOZ, 2 SAŞE, ALKA-SELTZER 324 MG/965 MG/1744 MG EFERVESAN TABLET, 10 ADETSterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating
go.drugbank.com/bio_entities/BE0000044TargetHumansCatalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis (By similarity).
Polypeptides: Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylatingLong-chain-fatty-acid--CoA ligase 4
go.drugbank.com/bio_entities/BE0000996TargetHumansCatalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:21242590, PubMed:22633490, PubMed:24269233, PubMed:31061331, PubMed:387201...
Polypeptides: Long-chain-fatty-acid--CoA ligase 4Synonyms: LACS 4, Long-chain acyl-CoA synthetase 4Sodium channel protein type 4 subunit alpha
go.drugbank.com/bio_entities/BE0002083TargetTransporterHumansPore-forming subunit of Nav1.4, a voltage-gated sodium (Nav) channel that directly mediates the depolarizing phase of action potentials in excitable membranes. Navs, also called VGSCs (voltage-gated sodium channels) or VDSCs (voltage-dep...
Polypeptides: Sodium channel protein type 4 subunit alphaVery long chain fatty acid elongase 4
go.drugbank.com/bio_entities/BE0002247EnzymeTargetHumansCatalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- a...
Polypeptides: Very long chain fatty acid elongase 4Synonyms: ELOVL FA elongase 4, ELOVL fatty acid elongase 4Calcium-activated potassium channel subunit beta-4
go.drugbank.com/bio_entities/BE0004424TargetHumansRegulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium se...
Polypeptides: Calcium-activated potassium channel subunit beta-4Synonyms: Slo-beta-4, K(VCA)beta-4Mitogen-activated protein kinase kinase kinase 4
go.drugbank.com/bio_entities/BE0009468TargetHumansComponent of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6
Polypeptides: Mitogen-activated protein kinase kinase kinase 4Synonyms: MEKK 4, MEK kinase 4Myosin light chain kinase family member 4
go.drugbank.com/bio_entities/BE0009494TargetHumansPolypeptides: Myosin light chain kinase family member 4Insulin-like growth factor-binding protein 4
go.drugbank.com/bio_entities/BE0009660CarrierHumansIGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors
Polypeptides: Insulin-like growth factor-binding protein 4Synonyms: IBP-4, IGFBP-4Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2
go.drugbank.com/bio_entities/BE0015894EnzymeHumansBifunctional enzyme which acts both as a sphingolipid delta(4)-desaturase and a sphingolipid C4-monooxygenase
Polypeptides: Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2Synonyms: Sphingolipid 4-desaturase