Search

Displaying results 521 - 530 of 10000 in total
  1. Pathway

    Metabolism and Physiological Effects of S-Adenosylhomocysteine

    smpdb.ca/view/SMP0127690
    Metabolic

    S-Adenosyl-L-homocysteine (SAH) is formed by the demethylation of S-adenosyl-L-methionine. … S-Adenosylhomocysteine forms when there are elevated levels of homocysteine and adenosine. S-Adenosyl-L-homocysteine is a potent inhibitor of S-adenosyl-L-methionine-dependent methylation reactions.

    Drugs: Ademetionine · Methionine · ATP · Potassium cation · Magnesium cation · Pyrophosphoric acid
    Enzymes: S-methylmethionine--homocysteine S-methyltransferase BHMT2, S-adenosylmethionine synthase isoform type-2
  2. Drug

    A-16L

    go.drugbank.com/drugs/DB18270
    Experimental

    Synonyms: MAVEROPEPIMUT-S COMPONENT A16L, L-ALANYL-L-GLUTAMINYL-L-TYROSYL-L-ISOLEUCYL-L-LYSYL-L-ALANYL-L-ASPARAGINYL-L-SERYL-L-LYSYL-L-PHENYLALANYL-L-ISOLEUCYLGLYCYL-L-ISOLEUCYL-L-THREONYL-L-.ALPHA.-GLUTAMYL-L-LEUCINE
  3. Drug

    Butylscopolamine

    go.drugbank.com/drugs/DB09300
    ApprovedInvestigationalVet approved

    Butylscopolamine is a peripherally acting antimuscarinic, anticholinergic agent. … It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.

    Mixtures: TRANKO-BUSKAS 10 MG + 10 MG KAPLI TABLET, 40 ADET, TRANKO-BUSKAS 10 MG + 10 MG KAPLI TABLET, 20 ADETSynonyms: N-butylscopolammonium, N-butylscopolammonium ion
  4. Drug

    Acazicolcept

    go.drugbank.com/drugs/DB18410
    Investigational

    Synonyms: (133-363) VARIANT (C137>S, L151>A, L152>E, G154>A,, .1-CHAIN C REGION VARIANT C-TERMINAL FRAGMENT), DIMER
  5. Drug

    JNJ-55308942

    go.drugbank.com/drugs/DB19110
    Investigational

    JNJ-55308942 is under investigation in clinical trial NCT05328297 (A Study of JNJ-55308942 in the Treatment of Bipolar Depression).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: (S)-(3-Fluoro-2-(trifluoromethyl)pyridin-4-yl)(1-(5-fluoropyrimidin-2-yl)-6-methyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridin-5(4H)-yl)methanone, ((6S)-1-(5-FLUORO-2-PYRIMIDINYL)-1,4,6,7-TETRAHYDRO-6-METHYL-5H-1,2,3-TRIAZOLO(4,5-C)PYRIDIN-5-YL)(3-FLUORO-2-(TRIFLUOROMETHYL)-4-PYRIDINYL)METHANONE
  6. Target

    Cathepsin S

    go.drugbank.com/bio_entities/BE0001646
    TargetHumans

    Thiol protease (PubMed:30612035). Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation (PubMed:30612035). The bond-specificity of this proteinase is in part sim...

    Polypeptides: Cathepsin S
  7. Target

    Aminopeptidase S

    go.drugbank.com/bio_entities/BE0002747
    TargetStreptomyces griseus

    An exopeptidase specific for larger hydrophobic amino acids (especially leucine), no cleavage occurs if the next residue is proline (PubMed:8444149).

    Polypeptides: Aminopeptidase S
  8. Target

    S-methylmethionine--homocysteine S-methyltransferase BHMT2

    go.drugbank.com/bio_entities/BE0002249
    TargetEnzymeHumans

    Converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor

    Polypeptides: S-methylmethionine--homocysteine S-methyltransferase BHMT2Synonyms: Betaine--homocysteine S-methyltransferase 2
  9. Drug

    Elenestinib

    go.drugbank.com/drugs/DB18489
    Investigational

    Elenestinib is a selective KIT inhibitor.

    Synonyms: (S)-2-(4-(4-(4-(5-(1-amino-1-(4-fluorophenyl)ethyl)pyrimidin-2-yl)piperazin-1-yl)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-1H-pyrazol-1-yl)ethan-1-ol, 1H-Pyrazole-1-ethanol, 4-[4-[4-[5-[(1S)-1-amino-1-(4-fluorophenyl)ethyl]-2-pyrimidinyl]-1-piperazinyl]pyrrolo[2,1-f][1,2,4]triazin-6-yl]-
  10. Target

    Neuropeptide S receptor

    go.drugbank.com/bio_entities/BE0000948
    TargetHumans

    G protein-coupled receptor for neuropeptide S (NPS) (PubMed:15947423, PubMed:16720571, PubMed:16790440).

    Polypeptides: Neuropeptide S receptor