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Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase
go.drugbank.com/bio_entities/BE0001689TargetMycobacterium tuberculosisCatalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.
Polypeptides: Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolaseFunction: 4-hydroxy-4-methyl-2-oxoglutarate aldolase activityPhospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive
go.drugbank.com/bio_entities/BE0002004TargetEscherichia coli (strain K12)Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
Polypeptides: Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitiveSynonyms: Phospho-2-keto-3-deoxyheptonate aldolaseGamma-aminobutyric acid type B receptor subunit 2
go.drugbank.com/bio_entities/BE0002340TargetHumansComponent of a heterodimeric G protein-coupled receptor for GABA, formed by GABBR1 and GABBR2 (PubMed:15617512, PubMed:18165688, PubMed:22660477, PubMed:24305054, PubMed:9872316, PubMed:9872744). Within the heterodimeric GABA receptor, o...
Polypeptides: Gamma-aminobutyric acid type B receptor subunit 2Synonyms: GABA-B receptor 22-oxo-1,2-dihydroquinoline 8-monooxygenase, oxygenase component
go.drugbank.com/bio_entities/BE0003357TargetPseudomonas putidaPolypeptides: 2-oxo-1,2-dihydroquinoline 8-monooxygenase, oxygenase componentFunction: 2 iron, 2 sulfur cluster binding6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4
go.drugbank.com/bio_entities/BE0003931TargetHumansSynthesis and degradation of fructose 2,6-bisphosphate
Polypeptides: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4Synonyms: 6PF-2-K/Fru-2,6-P2ase 4, 6PF-2-K/Fru-2,6-P2ase testis-type isozyme2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
go.drugbank.com/bio_entities/BE0004106TargetEscherichia coli (strain K12)Also converts 4-diphosphocytidyl-2-C-methyl-D-erythritol into 2-C-methyl-D-erythritol 3,4-cyclophosphate and CMP. … Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate
Polypeptides: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthaseFunction: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activityDehydrogenase/reductase SDR family member 4-like 2
go.drugbank.com/bio_entities/BE0004192TargetHumansProbable oxidoreductase
Polypeptides: Dehydrogenase/reductase SDR family member 4-like 2Actin-related protein 2/3 complex subunit 4
go.drugbank.com/bio_entities/BE0004254TargetHumansActin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin ...
Polypeptides: Actin-related protein 2/3 complex subunit 4Actin-related protein 2/3 complex subunit 5
go.drugbank.com/bio_entities/BE0004255TargetHumansComponent of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in th...
Polypeptides: Actin-related protein 2/3 complex subunit 5[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial
go.drugbank.com/bio_entities/BE0004348TargetHumansKinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby re...
Polypeptides: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrialSynonyms: PDH kinase 2, Pyruvate dehydrogenase kinase isoform 2