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S-methylmethionine--homocysteine S-methyltransferase BHMT2
go.drugbank.com/bio_entities/BE0002249TargetEnzymeHumansConverts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor
Polypeptides: S-methylmethionine--homocysteine S-methyltransferase BHMT2Synonyms: Betaine--homocysteine S-methyltransferase 2Acazicolcept
go.drugbank.com/drugs/DB18410InvestigationalSynonyms: (133-363) VARIANT (C137>S, L151>A, L152>E, G154>A,, .1-CHAIN C REGION VARIANT C-TERMINAL FRAGMENT), DIMERJNJ-55308942
go.drugbank.com/drugs/DB19110InvestigationalJNJ-55308942 is under investigation in clinical trial NCT05328297 (A Study of JNJ-55308942 in the Treatment of Bipolar Depression).
Categories: Heterocyclic Compounds, 1-RingSynonyms: (S)-(3-Fluoro-2-(trifluoromethyl)pyridin-4-yl)(1-(5-fluoropyrimidin-2-yl)-6-methyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridin-5(4H)-yl)methanone, ((6S)-1-(5-FLUORO-2-PYRIMIDINYL)-1,4,6,7-TETRAHYDRO-6-METHYL-5H-1,2,3-TRIAZOLO(4,5-C)PYRIDIN-5-YL)(3-FLUORO-2-(TRIFLUOROMETHYL)-4-PYRIDINYL)METHANONEEuropean pilchard
go.drugbank.com/drugs/DB10622ApprovedEuropean pilchard allergenic extract is used in allergenic testing.
Synonyms: European pilchardElenestinib
go.drugbank.com/drugs/DB18489InvestigationalElenestinib is a selective KIT inhibitor.
Synonyms: (S)-2-(4-(4-(4-(5-(1-amino-1-(4-fluorophenyl)ethyl)pyrimidin-2-yl)piperazin-1-yl)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-1H-pyrazol-1-yl)ethan-1-ol, 1H-Pyrazole-1-ethanol, 4-[4-[4-[5-[(1S)-1-amino-1-(4-fluorophenyl)ethyl]-2-pyrimidinyl]-1-piperazinyl]pyrrolo[2,1-f][1,2,4]triazin-6-yl]-Neuropeptide S receptor
go.drugbank.com/bio_entities/BE0000948TargetHumansG protein-coupled receptor for neuropeptide S (NPS) (PubMed:15947423, PubMed:16720571, PubMed:16790440).
Polypeptides: Neuropeptide S receptorS-ribosylhomocysteine lyase
go.drugbank.com/bio_entities/BE0001462TargetDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
Polypeptides: S-ribosylhomocysteine lyaseS-formylglutathione hydrolase
go.drugbank.com/bio_entities/BE0002283TargetEnzymeHumansSerine hydrolase involved in the detoxification of formaldehyde
Polypeptides: S-formylglutathione hydrolase(S)-mandelate dehydrogenase
go.drugbank.com/bio_entities/BE0003028TargetEnzymePseudomonas putidaCatalyzes the dehydrogenation of (S)-mandelate to phenylglyoxylate (benzoylformate) (PubMed:10493804, PubMed:19465768).
Polypeptides: (S)-mandelate dehydrogenaseFunction: (S)-mandelate dehydrogenase activityBlasticidin-S deaminase
go.drugbank.com/bio_entities/BE0003364TargetAspergillus terreusCatalyzes the deamination of the cytosine moiety of the antibiotics blasticidin S, cytomycin and acetylblasticidin S.
Polypeptides: Blasticidin-S deaminaseFunction: blasticidin-S deaminase activity