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Interleukin-36 alpha
go.drugbank.com/bio_entities/BE0020856TargetHumans-8 and IL-6. … In cultured monocytes up-regulates expression of IL-1A, IL-1B and IL-6. In myeloid dendritic cells involved in cell maturation by up-regulating surface expression of CD83, CD86 and HLA-DR.
Synonyms: IL-1F6, IL-1 epsilonVinorelbine
go.drugbank.com/drugs/DB00361ApprovedInvestigationalIt was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. It is a third-generation vinca alkaloid. … Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) [L1998].
Products: RENOVEL 10 MG/1 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET, VINALINE 50 MG/5 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADETTetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate
go.drugbank.com/drugs/DB14106ApprovedInvestigationalTetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for assessing myocardial perfusion.[L12744]
Synonyms: Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate, Tetrakis (2-methoxyisobutyl isonitrile) copper (I) tetrafluoroborateProducts: MON.MIBI KIT, 1.0 MG/FLAKON IV ENJEKSİYON İÇİN STERİL/APİROJEN LİYOFİLİZE TOZ, 5 ADETThiotepa
go.drugbank.com/drugs/DB04572ApprovedInvestigationalIt is a stable derivative of N,N',N''- triethylenephosphoramide (TEPA). It is mostly used to treat breast cancer, ovarian cancer and bladder cancer. … It is also used as conditioning for Bone marrow transplantation. Its main toxicity is myelosuppression.
Synonyms: Tris(Aziridin-1-yl)-sulfanylideneλ5phosphaneProducts: TEPADİNA 100 MG IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADETOmeprazole
go.drugbank.com/drugs/DB00338ApprovedInvestigationalVet approvedOriginally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders. … Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults [FDA label].
Products: PRAZIDEC - I, OCID IV (INJECTION)Interleukin-18
go.drugbank.com/bio_entities/BE0010340TargetHumansPro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (PubMed:10653850). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary com...
Synonyms: IL-18, IL-1 gammaC-X-C chemokine receptor type 1
go.drugbank.com/bio_entities/BE0003552TargetHumansBinding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:8662698)
Synonyms: IL-8R A, IL-8 receptor type 1Trastuzumab
go.drugbank.com/drugs/DB00072ApprovedInvestigationalWhile Ogivri is the first biosimilar approved in the U.S. for the treatment of breast cancer or stomach cancer, it is the second biosimilar approved in the U.S. for the treatment of cancer. … -2 protein in tumours.
Products: HERCEPTIN (SOLUTION FOR INJECTION 600 MG/5 ML), HERZUMA 150 MG IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADETInterleukin-12 subunit beta
go.drugbank.com/bio_entities/BE0000981TargetHumansCytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC
Synonyms: IL-12B, IL-12 subunit p40Interleukin-12 subunit alpha
go.drugbank.com/bio_entities/BE0012862TargetHumansHeterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine (PubMed:8605935, PubMed:8943050). … As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and also functions as an immune-suppressive cytokine (By similarity).
Synonyms: IL-12A, IL-12 subunit p35