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Displaying results 5661 - 5670 of 10000 in total
  1. Target

    Trypsin-2

    go.drugbank.com/bio_entities/BE0004529
    TargetHumans

    In the ileum, may be involved in defensin processing, including DEFA5

    Polypeptides: Trypsin-2Synonyms: Serine protease 2
  2. Target

    Metallothionein-2

    go.drugbank.com/bio_entities/BE0004779
    EnzymeTargetHumans

    Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids

    Polypeptides: Metallothionein-2Synonyms: MT-2
  3. Target

    Stabilin-2

    go.drugbank.com/bio_entities/BE0004948
    TargetHumans

    Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Also acts, in different species, as a primary systemic scavenger receptor fo...

    Polypeptides: Stabilin-2Synonyms: FEEL-2, FAS1 EGF-like and X-link domain-containing adhesion molecule 2
  4. Target

    Fibrillin-2

    go.drugbank.com/bio_entities/BE0008694
    TargetHumans

    Fibrillin-2-containing microfibrils regulate the early process of elastic fiber assembly.

    Polypeptides: Fibrillin-2
  5. Target

    Calsequestrin-2

    go.drugbank.com/bio_entities/BE0008695
    TargetHumans

    Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction.

    Polypeptides: Calsequestrin-2
  6. Target

    Calmodulin-2

    go.drugbank.com/bio_entities/BE0008705
    TargetHumans

    Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding (PubMed:16760425, PubMed:26969752, PubMed:2716569...

    Polypeptides: Calmodulin-2
  7. Target

    Transgelin-2

    go.drugbank.com/bio_entities/BE0009122
    TargetHumans

    Polypeptides: Transgelin-2
  8. Target

    Caspase-2

    go.drugbank.com/bio_entities/BE0013189
    TargetHumans

    Is a regulator of the cascade of caspases responsible for apoptosis execution (PubMed:11156409, PubMed:15073321, PubMed:8087842). Might function by either activating some proteins required for cell death or inactivating proteins necessar...

    Polypeptides: Caspase-2Synonyms: CASP-2, NEDD-2
  9. Target

    Sestrin-2

    go.drugbank.com/bio_entities/BE0013521
    TargetHumans

    Functions as an intracellular leucine sensor that negatively regulates the mTORC1 signaling pathway through the GATOR complex (PubMed:18692468, PubMed:25263562, PubMed:25457612, PubMed:26449471, PubMed:26586190, PubMed:26612684, PubMed:3...

    Polypeptides: Sestrin-2
  10. Target

    Peroxiredoxin-2

    go.drugbank.com/bio_entities/BE0001972
    TargetHumans

    Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2)

    Polypeptides: Peroxiredoxin-2Synonyms: Thioredoxin-dependent peroxiredoxin 2