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Displaying results 5771 - 5780 of 10000 in total
  1. Drug

    Kaolin

    go.drugbank.com/drugs/DB01575
    Approved

    Kaolin is a layered silicate mineral. … Kaolin is used in ceramics, medicine, coated paper, as a food additive, in toothpaste, as a light diffusing material in white incandescent light bulbs, and in cosmetics.

    Mixtures: Pranicura 5, 2% Salicylic Acid FACIAL CLEANSERProducts: W Lab ALL CLEAR MINT PACK, Look At Me Mud Face Mask Mini Pack Aloe
  2. Drug

    Oxyphencyclimine

    go.drugbank.com/drugs/DB00383
    Approved

    Oxyphencyclimine is an anticholinergic drug (trade name Daricon) used in treating peptic ulcers.

    Categories: Heterocyclic Compounds, 1-RingProducts: ออกซี่เฟน 5, ยาเม็ด อ๊อกซีเฟนไซคลีมีน (5 มก.)
  3. Drug

    Reteplase

    go.drugbank.com/drugs/DB00015
    ApprovedInvestigationalWithdrawn

    Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains the activity-related kringle-2 and serine protease domains of human tPA. … Three domains are deleted from retavase - kringle-1, finger, and epidermal growth factor (EGF).

    Synonyms: Human t-PA (residues 1-3 and 176-527)Products: RAPILYSIN 10 U IV ENJ. ICIN STERIL LIYOFILIZE TOZ ICEREN FLAKON, 2 ADET
  4. Drug

    Fluvastatin

    go.drugbank.com/drugs/DB01095
    ApprovedInvestigational

    Fluvastatin is a racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. … Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase.

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP2B6 InducersProducts: Fluvastatin Sandoz 20 mg - Hartkapseln, LESCOL XL 80 MG TABLET, 28 ADET
  5. Drug

    Amphotericin B

    go.drugbank.com/drugs/DB00681
    ApprovedInvestigational

    While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. … ranging from 0.03 to 1.0 mcg/mL in vitro.

    Synonyms: AMPH-b, Amfotericina BSalts: Amphotericin B Cholesteryl Sulfate Complex
  6. Target

    2-methylisocitrate lyase

    go.drugbank.com/bio_entities/BE0001259
    TargetEscherichia coli (strain K12)

    Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). … Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

    Polypeptides: 2-methylisocitrate lyaseSynonyms: 2-MIC, (2R,3S)-2-methylisocitrate lyase
  7. Target

    2-hydroxymuconate tautomerase

    go.drugbank.com/bio_entities/BE0001410
    TargetPseudomonas putida

    Catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate.

    Polypeptides: 2-hydroxymuconate tautomerase
  8. Target

    Tryptase beta-2

    go.drugbank.com/bio_entities/BE0001474
    TargetHumans

    Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity

    Polypeptides: Tryptase beta-2Synonyms: Tryptase-2
  9. Target

    Peptide deformylase 2

    go.drugbank.com/bio_entities/BE0001645
    TargetGeobacillus stearothermophilus

    Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity ...

    Polypeptides: Peptide deformylase 2Synonyms: PDF 2, Polypeptide deformylase 2
  10. Target

    2-isopropylmalate synthase

    go.drugbank.com/bio_entities/BE0001742
    TargetMycobacterium tuberculosis

    Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (alpha-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (PubMed:11914056, PubMed … Active on small alpha-keto acids such as 3-methyl-2-oxobutanoate, pyruvate, alpha-ketovalerate, and alpha-ketobutyrate; only uses acetyl-CoA (PubMed:16846242).

    Polypeptides: 2-isopropylmalate synthaseFunction: 2-isopropylmalate synthase activity