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Displaying results 571 - 580 of 10000 in total
  1. Target

    Glutathione S-transferase Mu 4

    go.drugbank.com/bio_entities/BE0000812
    TargetHumans

    Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator

    Polypeptides: Glutathione S-transferase Mu 4
  2. Target

    Glutathione S-transferase omega-1

    go.drugbank.com/bio_entities/BE0000815
    TargetEnzymeHumans

    Has S-(phenacyl)glutathione reductase activity. Also has glutathione S-transferase activity.

    Polypeptides: Glutathione S-transferase omega-1Synonyms: Glutathione S-transferase omega 1-1, S-(Phenacyl)glutathione reductase
  3. Target

    Betaine--homocysteine S-methyltransferase 1

    go.drugbank.com/bio_entities/BE0000845
    TargetHumans

    Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline

    Polypeptides: Betaine--homocysteine S-methyltransferase 1Function: betaine-homocysteine S-methyltransferase activity
  4. Target

    Glutathione S-transferase Mu 2

    go.drugbank.com/bio_entities/BE0001189
    TargetEnzymeHumans

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276)

    Polypeptides: Glutathione S-transferase Mu 2
  5. Target

    5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

    go.drugbank.com/bio_entities/BE0002007
    TargetEscherichia coli (strain K12)

    and S-ribosylhomocysteine, respectively (PubMed:16101288, PubMed:3911944). … Can also use 5'-isobutylthioadenosine, 5'-n-butylthioadenosine, S-adenosyl-D-homocysteine, decarboxylated adenosylhomocysteine, deaminated adenosylhomocysteine and S-2-aza-adenosylhomocysteine as substrates

    Polypeptides: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidaseSynonyms: S-adenosylhomocysteine nucleosidase
  6. Target

    5-methyltetrahydrofolate--homocysteine S-methyltransferase

    go.drugbank.com/bio_entities/BE0002812
    TargetMoorella thermoacetica (strain ATCC 39073)

    Polypeptides: 5-methyltetrahydrofolate--homocysteine S-methyltransferase
  7. Indication

    Moderate, active Crohn´s Disease

    go.drugbank.com/conditions/DBCOND0123592
    Drugs: Guselkumab · Risankizumab · Upadacitinib · Ustekinumab
    Synonyms: Moderate, active Crohn´s Disease
  8. Drug

    Betaxolol

    go.drugbank.com/drugs/DB00195
    ApprovedInvestigational

    A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.

    Synonyms: 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol, 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanolCategories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor Antagonists
  9. Drug

    Clofibrate

    go.drugbank.com/drugs/DB00636
    ApprovedWithdrawn

    A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)

    Synonyms: 2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester, 2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl esterInternational brands: Atromid-S
  10. Drug

    Sulfamethizole

    go.drugbank.com/drugs/DB00576
    ApprovedVet approved

    A sulfathiazole antibacterial agent.

    Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: S*ORIPOL FORTE®., S- URISTIX 500 MG CAPSULAS