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Displaying results 5821 - 5830 of 10000 in total
  1. Target

    Heparin cofactor 2

    go.drugbank.com/bio_entities/BE0000775
    TargetHumans

    Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but i...

    Polypeptides: Heparin cofactor 2Synonyms: Protease inhibitor leuserpin-2
  2. Target

    Glutathione peroxidase 2

    go.drugbank.com/bio_entities/BE0000817
    TargetHumans

    Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis (PubMed:36608588, PubMed:8428933). Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert...

    Polypeptides: Glutathione peroxidase 2Synonyms: GPx-2, GPRP-2
  3. Target

    Alpha-2-macroglobulin

    go.drugbank.com/bio_entities/BE0000910
    TargetCarrierHumans

    Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves...

    Polypeptides: Alpha-2-macroglobulinSynonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, Alpha-2-M
  4. Target

    Inositol monophosphatase 2

    go.drugbank.com/bio_entities/BE0000983
    TargetHumans

    Phosphatase that can use myo-inositol monophosphates, myo-inositol 1,4-diphosphate, scyllo-inositol-1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate and 2'-AMP as substrates in vitro (PubMed

    Polypeptides: Inositol monophosphatase 2Synonyms: IMP 2, IMPase 2
  5. Target

    Neuroendocrine convertase 2

    go.drugbank.com/bio_entities/BE0002124
    EnzymeHumans

    Serine endopeptidase which is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues (PubMed:28719828, PubMed:7626024, PubMed:8879041, PubMed:9287128). Responsible for ...

    Polypeptides: Neuroendocrine convertase 2Synonyms: NEC 2, KEX2-like endoprotease 2
  6. Target

    P2Y purinoceptor 2

    go.drugbank.com/bio_entities/BE0002401
    TargetHumans

    The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP

    Polypeptides: P2Y purinoceptor 2
  7. Target

    2-methylcitrate synthase

    go.drugbank.com/bio_entities/BE0002690
    TargetAntarctic bacterium DS2-3R

    Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA. … Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route).

    Polypeptides: 2-methylcitrate synthaseSynonyms: 2-MCS, (2S,3S)-2-methylcitrate synthase
  8. Target

    Nucleoside 2-deoxyribosyltransferase

    go.drugbank.com/bio_entities/BE0003329
    TargetTrypanosoma brucei brucei (strain 927/4 GUTat10.1)

    Polypeptides: Nucleoside 2-deoxyribosyltransferaseFunction: deoxyribonucleoside 5'-monophosphate N-glycosidase activity
  9. Target

    Alpha-mannosidase 2

    go.drugbank.com/bio_entities/BE0003505
    TargetHumans

    Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway

    Polypeptides: Alpha-mannosidase 2
  10. Target

    Beta-2-microglobulin

    go.drugbank.com/bio_entities/BE0003777
    TargetCarrierHumans

    Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decrea...

    Polypeptides: Beta-2-microglobulin