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Displaying results 581 - 590 of 10000 in total
  1. Target

    Glutathione S-transferase Mu 3

    go.drugbank.com/bio_entities/BE0000810
    TargetEnzymeHumans

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers

    Polypeptides: Glutathione S-transferase Mu 3
  2. Target

    Glutathione S-transferase Mu 4

    go.drugbank.com/bio_entities/BE0000812
    TargetHumans

    Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator

    Polypeptides: Glutathione S-transferase Mu 4
  3. Target

    Glutathione S-transferase omega-1

    go.drugbank.com/bio_entities/BE0000815
    TargetEnzymeHumans

    Has S-(phenacyl)glutathione reductase activity. Also has glutathione S-transferase activity.

    Polypeptides: Glutathione S-transferase omega-1Synonyms: Glutathione S-transferase omega 1-1, S-(Phenacyl)glutathione reductase
  4. Target

    Betaine--homocysteine S-methyltransferase 1

    go.drugbank.com/bio_entities/BE0000845
    TargetHumans

    Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline

    Polypeptides: Betaine--homocysteine S-methyltransferase 1Function: betaine-homocysteine S-methyltransferase activity
  5. Target

    Glutathione S-transferase Mu 2

    go.drugbank.com/bio_entities/BE0001189
    TargetEnzymeHumans

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276)

    Polypeptides: Glutathione S-transferase Mu 2
  6. Target

    5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

    go.drugbank.com/bio_entities/BE0002007
    TargetEscherichia coli (strain K12)

    and S-ribosylhomocysteine, respectively (PubMed:16101288, PubMed:3911944). … Can also use 5'-isobutylthioadenosine, 5'-n-butylthioadenosine, S-adenosyl-D-homocysteine, decarboxylated adenosylhomocysteine, deaminated adenosylhomocysteine and S-2-aza-adenosylhomocysteine as substrates

    Polypeptides: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidaseSynonyms: S-adenosylhomocysteine nucleosidase
  7. Target

    5-methyltetrahydrofolate--homocysteine S-methyltransferase

    go.drugbank.com/bio_entities/BE0002812
    TargetMoorella thermoacetica (strain ATCC 39073)

    Polypeptides: 5-methyltetrahydrofolate--homocysteine S-methyltransferase
  8. Drug

    Dorzolamide

    go.drugbank.com/drugs/DB00869
    ApprovedInvestigational

    Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and … [A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt [L11377] or in combination with [timolol] as Cosopt PF.[L11380]

    Synonyms: (4S,6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid amide, (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxideMixtures: COSOPT S 20/5MG/ML, COSOPT S 20MG/ML+5MG/ML
  9. Indication

    Typhoid Fever caused by S. typhi

    go.drugbank.com/conditions/DBCOND0093736
    Drugs: Typhoid Vi polysaccharide vaccine
    Synonyms: Typhoid Fever caused by S. typhi
  10. Drug

    Acebutolol

    go.drugbank.com/drugs/DB01193
    ApprovedInvestigational

    The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action. … A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamide, 3'-acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide