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Estazolam
go.drugbank.com/drugs/DB01215ApprovedIllicitInvestigationalA benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingSynonyms: 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepineSphingosine-1-phosphate lyase 1
go.drugbank.com/bio_entities/BE0000778TargetHumansCleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine.
Polypeptides: Sphingosine-1-phosphate lyase 1Synonyms: SPL 1, SP-lyase 1Alpha-1-acid glycoprotein 1
go.drugbank.com/bio_entities/BE0000925CarrierTargetHumansFunctions as a transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modu...
Polypeptides: Alpha-1-acid glycoprotein 1Synonyms: AGP 1, OMD 11-aminocyclopropane-1-carboxylate deaminase
go.drugbank.com/bio_entities/BE0001378TargetPseudomonas sp. (strain ACP)Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source.
Polypeptides: 1-aminocyclopropane-1-carboxylate deaminaseFunction: 1-aminocyclopropane-1-carboxylate deaminase activitySphingosine 1-phosphate receptor 1
go.drugbank.com/bio_entities/BE0008652TargetHumansRequired for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. … G protein-coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins.
Polypeptides: Sphingosine 1-phosphate receptor 1Synonyms: Sphingosine 1-phosphate receptor Edg-1, S1P receptor 1Previously treated with an HCV regimen containing an NS5A inhibitor Chronic hepatitis C genotype 5
go.drugbank.com/conditions/DBCOND0093778Drugs: VoxilaprevirSynonyms: Previously treated with an HCV regimen containing an NS5A inhibitor Chronic hepatitis C genotype 5Teniposide
go.drugbank.com/drugs/DB00444ApprovedInvestigationalTeniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. … Accumulated breaks in DNA prevent cells from entering into the mitotic phase of the cell cycle, and lead to cell death. Teniposide acts primarily in the G2 and S phases of the cycle.
Categories: Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 4'-demethylepipodophyllotoxin 9-(4,6-O-(R)-2-thenylidene-beta-D-glucopyranoside)Brodalumab
go.drugbank.com/drugs/DB11776ApprovedInvestigationalBrodalumab was FDA approved in February, 2017 as Siliq for the treatment of moderate-to-severe plaque psoriasis. … Brodalumab has been used in trials studying the treatment of Asthma, Psoriasis, Crohn's Disease, Psoriatic Arthritis, and Rheumatoid Arthritis.
Categories: Interleukin-17 Receptor A Antagonist, Interleukin 17 Receptor A AntagonistsProducts: LUMICEF SUBCUTANEOUS INJECTION 210 MG SYRINGELactose
go.drugbank.com/drugs/DB04465ApprovedInvestigationalWithdrawnA disaccharide of glucose and galactose in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.
Mixtures: SYNTHROID® 112 MCG TABLETAS, SERECOR® FORTE DPI 100Categories: Compounds used in a research, industrial, or household settingAluminum chloride
go.drugbank.com/drugs/DB11081ApprovedInvestigationalAluminum chloride is a chemical compound with the chemical formula AlCl3. When contaminated with iron chloride, it often displays a yellow color compared to the white pure compound. … It is used in various chemical applications as a Lewis base, with anhydrous aluminium trichloride being the most commonly used Lewis acid.
Mixtures: Anti-perspirant Roll-ON Deod, Youth Dew Roll On Antipersp Deod LotCategories: Compounds used in a research, industrial, or household setting