Search

Displaying results 611 - 620 of 1186 in total
  1. Target

    Glycine receptor (alpha-1/beta)

    go.drugbank.com/bio_entities/BE0004857
    TargetHumans

    Subunit of heteromeric glycine-gated chloride channels (PubMed:14551753, PubMed:23994010, PubMed:25730860, PubMed:37821459). Plays an important role in the down-regulation of neuronal excitability (PubMed:8298642, PubMed:9009272). Contri...

    Polypeptides: Glycine receptor subunit beta, Glycine receptor subunit alpha-1Synonyms: Glycine receptor 48 kDa subunit, Glycine receptor 58 kDa subunit
  2. Target

    Sphingosine 1-phosphate receptor 1

    go.drugbank.com/bio_entities/BE0008652
    TargetHumans

    G protein-coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins.

    Polypeptides: Sphingosine 1-phosphate receptor 1Synonyms: S1P receptor 1, S1P receptor Edg-1
  3. Target

    G protein-coupled receptor 12

    go.drugbank.com/bio_entities/BE0009153
    TargetHumans

    Functions as a receptor with constitutive G(s)-mediated signaling activity that stimulates cyclic AMP (cAMP) production (PubMed:36593162). … Brain-specific G protein-coupled receptor involved in regulating diverse physiological processes including neurite outgrowth, meiotic arrest, and lipid and carbohydrate metabolism (By similarity).

    Polypeptides: G protein-coupled receptor 12Function: G protein-coupled receptor activity
  4. Target

    Tyrosine-protein kinase receptor TYRO3

    go.drugbank.com/bio_entities/BE0009404
    TargetHumans

    Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6.

    Polypeptides: Tyrosine-protein kinase receptor TYRO3
  5. Target

    Ephrin type-A receptor 1

    go.drugbank.com/bio_entities/BE0009436
    TargetHumans

    The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. … Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.

    Polypeptides: Ephrin type-A receptor 1Synonyms: Tyrosine-protein kinase receptor EPH, Erythropoietin-producing hepatoma receptor
  6. Target

    Ephrin type-A receptor 8

    go.drugbank.com/bio_entities/BE0009440
    TargetHumans

    Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. … The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.

    Polypeptides: Ephrin type-A receptor 8Synonyms: Tyrosine-protein kinase receptor EEK
  7. Target

    Ephrin type-B receptor 1

    go.drugbank.com/bio_entities/BE0009441
    TargetHumans

    Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. … Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.

    Polypeptides: Ephrin type-B receptor 1Synonyms: Tyrosine-protein kinase receptor EPH-2
  8. Target

    NT-3 growth factor receptor

    go.drugbank.com/bio_entities/BE0009501
    TargetHumans

    Receptor tyrosine kinase involved in nervous system and probably heart development.

    Polypeptides: NT-3 growth factor receptorSynonyms: Neurotrophic tyrosine kinase receptor type 3
  9. Target

    Receptor for retinol uptake STRA6

    go.drugbank.com/bio_entities/BE0009879
    TransporterHumans

    Functions as a retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding prot...

    Polypeptides: Receptor for retinol uptake STRA6Synonyms: Retinol-binding protein receptor STRA6
  10. Target

    Sphingosine 1-phosphate receptor 4

    go.drugbank.com/bio_entities/BE0009882
    TargetHumans

    Functions as a receptor for the lysosphingolipid sphingosine-1-phosphate (S1P). … G protein-coupled receptor highly expressed in immune cells, where it regulates immune response and cytokine production.

    Polypeptides: Sphingosine 1-phosphate receptor 4Synonyms: S1P receptor 4, S1P receptor Edg-6