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3-oxo-5-alpha-steroid 4-dehydrogenase 2
go.drugbank.com/bio_entities/BE0000585TargetEnzymeHumansCatalyzes the irreversible stereospecific reduction of the delta 4,5 bond (double bond between carbons 4 and 5) of various 3-oxo steroids (3-keto steroids) producing their 5alpha dihydro-3-oxo forms (PubMed
Polypeptides: 3-oxo-5-alpha-steroid 4-dehydrogenase 2Function: 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP+) activity4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
go.drugbank.com/bio_entities/BE0001574TargetShigella flexneriCatalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
Polypeptides: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinaseSynonyms: 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinaseCytochrome c oxidase subunit 4 isoform 1, mitochondrial
go.drugbank.com/bio_entities/BE0003986TargetHumansThe BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix
Polypeptides: Cytochrome c oxidase subunit 4 isoform 1, mitochondrialDehydrogenase/reductase SDR family member 4-like 2
go.drugbank.com/bio_entities/BE0004192TargetHumansProbable oxidoreductase
Polypeptides: Dehydrogenase/reductase SDR family member 4-like 2Actin-related protein 2/3 complex subunit 4
go.drugbank.com/bio_entities/BE0004254TargetHumansActin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin ...
Polypeptides: Actin-related protein 2/3 complex subunit 4[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial
go.drugbank.com/bio_entities/BE0004284TargetHumansKinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regula...
Polypeptides: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrialSynonyms: Pyruvate dehydrogenase kinase isoform 4Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
go.drugbank.com/bio_entities/BE0009517TargetHumansParticipates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate (PubMed:26774281, PubMed:9038203). Preferentially utilizes GTP, rather than ATP, for PI(5)P phosphorylation and its activity reflects changes in direct proportion ...
Polypeptides: Phosphatidylinositol 5-phosphate 4-kinase type-2 betaSynonyms: PI(5)P 4-kinase type II beta, PtdIns(5)P-4-kinase isoform 2-betaPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma
go.drugbank.com/bio_entities/BE0009518TargetHumansPhosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity.
Polypeptides: Phosphatidylinositol 5-phosphate 4-kinase type-2 gammaSynonyms: PI(5)P 4-kinase type II gamma, Phosphatidylinositol 5-phosphate 4-kinase type II gammacAMP-specific 3',5'-cyclic phosphodiesterase 4 (PDE4)
go.drugbank.com/bio_entities/BE0009963TargetHumansHydrolyzes the second messenger 3',5'-cyclic AMP (cAMP), which is a key regulator of many important physiological processes
Leukocyte immunoglobulin-like receptor subfamily B member 4
go.drugbank.com/bio_entities/BE0017129TargetHumansInhibitory receptor involved in the down-regulation of the immune response and the development of immune tolerance (PubMed:11875462). Receptor for FN1 (PubMed:34089617). Receptor for apolipoprotein APOE (PubMed:30333625). Receptor for AL...
Polypeptides: Leukocyte immunoglobulin-like receptor subfamily B member 4