Search

Displaying results 6341 - 6350 of 10000 in total
  1. Target

    Glycylpeptide N-tetradecanoyltransferase 2

    go.drugbank.com/bio_entities/BE0003780
    TargetHumans

    Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3' (PubMed:32103017).

    Polypeptides: Glycylpeptide N-tetradecanoyltransferase 2Synonyms: NMT 2, Peptide N-myristoyltransferase 2
  2. Target

    Thymidine kinase 2, mitochondrial

    go.drugbank.com/bio_entities/BE0004639
    TargetEnzymeHumans

    Phosphorylates thymidine, deoxycytidine, and deoxyuridine in the mitochondrial matrix (PubMed:11687801, PubMed:9989599). In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on TK2 an...

    Polypeptides: Thymidine kinase 2, mitochondrialSynonyms: 2'-deoxyuridine kinase TK2
  3. Target

    Secreted aspartic protease 2

    go.drugbank.com/bio_entities/BE0004793
    TargetYeast

    Secreted aspartic peptidases (SAPs) are a group of ten acidic hydrolases considered as key virulence factors (PubMed:11478679, PubMed:12761103, PubMed:15820985, PubMed:15845479, PubMed:19880183, PubMed:20713630, PubMed:22302440, PubMed:2...

    Polypeptides: Secreted aspartic protease 2Synonyms: ACP 2, Candidapepsin-2
  4. Target

    Interphotoreceptor matrix proteoglycan 2

    go.drugbank.com/bio_entities/BE0004942
    TargetHumans

    Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin

    Polypeptides: Interphotoreceptor matrix proteoglycan 2
  5. Target

    Endonuclease 8-like 2

    go.drugbank.com/bio_entities/BE0005817
    TargetHumans

    Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. … Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates

    Polypeptides: Endonuclease 8-like 2Synonyms: Nei homolog 2, Nei-like protein 2
  6. Target

    Orexin receptor type 2

    go.drugbank.com/bio_entities/BE0005865
    TargetHumans

    G protein-coupled receptor that binds neuropeptides orexin-A and orexin-B, two neuropeptides derived from a common precursor, prepro-orexin (PubMed:26950369, PubMed:33547286, PubMed:35614071, PubMed:9491897). Upon neuropeptide ligand bin...

    Polypeptides: Orexin receptor type 2Synonyms: Ox-2-R, Hypocretin receptor type 2
  7. Target

    Penicillin-binding protein 2

    go.drugbank.com/bio_entities/BE0008389
    TargetStaphylococcus aureus

    Polypeptides: Penicillin-binding protein 2
  8. Target

    Diacylglycerol O-acyltransferase 2

    go.drugbank.com/bio_entities/BE0008719
    EnzymeTargetHumans

    Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides (PubMe...

    Polypeptides: Diacylglycerol O-acyltransferase 2Synonyms: Diglyceride acyltransferase 2
  9. Target

    Alpha-2-HS-glycoprotein

    go.drugbank.com/bio_entities/BE0009048
    TargetHumans

    Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions

    Polypeptides: Alpha-2-HS-glycoproteinSynonyms: Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein
  10. Target

    LIM domain kinase 2

    go.drugbank.com/bio_entities/BE0009456
    TargetHumans

    Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics (PubMed:10436159, PubMed:11018042). Acts downstream of several Rho family GTPase signal transduction pathways (PubMed:10436159, Pub...

    Polypeptides: LIM domain kinase 2Synonyms: LIMK-2