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Displaying results 631 - 640 of 10000 in total
  1. Drug

    Vinorelbine

    go.drugbank.com/drugs/DB00361
    ApprovedInvestigational

    Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) [L1998]. … A study was done on the clearance rate of vinorelbine on individuals with various single polymorphonuclear mutations.

    Categories: Antineoplastic and Immunomodulating AgentsProducts: Vinobin Soft Capsules 20mg, NAVELBINE 20MG SOFT CAPSULE
  2. Drug

    Solenopsis invicta

    go.drugbank.com/drugs/DB10419
    Approved

    Solenopsis invicta allergenic extract is used in allergenic testing.

    Mixtures: Insects whole body, Fire Ant Mix, Insects whole body, Fire Ant MixCategories: Non-Standardized Insect Venom Allergenic Extract
  3. Drug

    Solenopsis richteri

    go.drugbank.com/drugs/DB11026
    Approved

    It is extracted from the black imported fire ant which is native to South Amercia. The species has also been introduced in North Amercia. … When stung, the bites are characterized by sterile pustules that are surrounded by reddened swelling along with redness extending beyond.

    Synonyms: black imported fire ant allergenic extractMixtures: Insects whole body, Fire Ant Mix, Insects whole body, Fire Ant Mix
  4. Drug

    Folic acid

    go.drugbank.com/drugs/DB00158
    ApprovedInvestigationalNutraceuticalVet approved

    [L5744] In order to function within the body, folic acid must first be reduced by the enzyme dihydrofolate reductase (DHFR) into the cofactors dihydrofolate (DHF) and tetrahydrofolate (THF). … This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is disrupted by anti-metabolite therapies such as [DB00563] as they function as DHFR inhibitors to prevent

    Synonyms: N-pteroyl-L-glutamic acid, N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acidMixtures: Folic Acid 1mg With C 20mg, Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo
  5. Drug

    Flurbiprofen

    go.drugbank.com/drugs/DB00712
    ApprovedInvestigational

    Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. … Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity.

    Mixtures: MAJEZIK DUO 100MG/8MG FILM KAPLI TABLET, TABLET, 14 ADETCategories: Antiinflammatory and Antirheumatic Products, Non-Steroids, Antiinflammatory and Antirheumatic Products
  6. Drug

    Sodium bicarbonate

    go.drugbank.com/drugs/DB01390
    ApprovedInvestigational

    Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

    Mixtures: MILACID® SACHET POR 10ML SABOR MENTA, Bicarbonate Concentrate No 4202 LiqCategories: Antacids and Adsorbents, Blood and Blood Forming Organs
  7. Pathway

    Metabolism and Physiological Effects of N-alpha-Acetyl-L-arginine

    smpdb.ca/view/SMP0125530
    Metabolic

    Arginnosuccinate is synthesized from citrulline and aspartic acid by the enzyme argininosuccinate synthase. That is catalyzed by argininosuccinate lyase to produce arginine and fumaric acid. … In the blood it works as a uremic toxin to cause kidney damage, cardiovascular disease and neurological deficits.

    Drugs: Pyridoxal phosphate · Arginine · Aspartic acid · Ornithine · L-Glutamine · Adenosine phosphate +10 more
  8. Pathway

    Ziconotide NMDA and Substance P Receptor Pain Inhibition Action Pathway

    smpdb.ca/view/SMP0126347
    Drug action

    such as intrathecal morphine and systemic analgesics. … This causes downstream nociceptive neuronal activity and pain perception. Substance P and CGRP both also induce inflammation, further exasperating chronic pain.

    Drugs: Glutamic acid · Calcium · Sar9, Met (O2)11-Substance P · Ziconotide
  9. Drug

    Chloramphenicol

    go.drugbank.com/drugs/DB00446
    ApprovedInvestigationalVet approvedWithdrawn

    An antibiotic first isolated from cultures of _Streptomyces venezuelae_ in 1947 but now produced synthetically. … It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic.

    Mixtures: CLOXONA-OCategories: Genito Urinary System and Sex Hormones, Gynecological Antiinfectives and Antiseptics
  10. Drug

    Butabarbital

    go.drugbank.com/drugs/DB00237
    ApprovedIllicitWithdrawn

    [A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety. … [A19735] Its short duration of action gives butabarbital a high abuse potential, comparable to [secobarbital].[A201977,A201980] Butabarbital was granted FDA approval on 5 June 1939.[L13613]

    Mixtures: Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and ButabarbitalCategories: Hypnotics and Sedatives